Cyclic variation in heart rate during sleep in four recordings of up to 13 years in elderly adults

P. K. Stein, R. J. Cohen, N. M. Devlin, E. M. Lundequam, P. P. Domitrovich, J. S. Gottdiener, S. R. Redline

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


To characterize changes in nighttime cyclic variation in HR (CVHR) with advancing age in older adults, CVHR was quantified for N=56 adults with 2 Holter recordings 5 yrs apart (CHS1 and CHS 2) in the Cardiovascular Health Study (CHS) and 2 overnight polysomnograms 5 yrs apart in the Sleep Heart Health Study (SHHS1 and SHHS2) using MatLab. Baseline age was 71±3yrs. The number of CVHR events was also normalized to time in bed (CVHR Index). CVHR Index did not change across recordings, but males had higher values (p=0.009). Mean HR increase during CVHR was similar in the first 3 recording but declined on the last (p<0.02). CVHR duration increased, but CHS1 vs. CHS2 and SHHS1 vs. SHHS2 were NS (rest, p<0.007). We conclude that CVHR is frequent at night in older adults, but results suggest an age-related trend towards decreased magnitude and longer durations of HR arousals, possibly due to the aging of the autonomic nervous system.

Original languageEnglish
Title of host publicationComputers in Cardiology 2007, CAR 2007
Number of pages3
StatePublished - 2007
EventComputers in Cardiology 2007, CAR 2007 - Durham, NC, United States
Duration: Sep 30 2007Oct 3 2007

Publication series

NameComputers in Cardiology
ISSN (Print)0276-6574


ConferenceComputers in Cardiology 2007, CAR 2007
Country/TerritoryUnited States
CityDurham, NC


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