Customizing a commercial rule base for detecting drug-drug interactions.

Ervina Resetar, Richard M. Reichley, Laura A. Noirot, Wm Claiborne Dunagan, Thomas C. Bailey

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


We developed and implemented an adverse drug event system (PharmADE) that detects potentially dangerous drug combinations using a commercial rule base. While commercial rule bases can be useful for rapid deployment of a safety net to screen for drug-drug interactions, they sometimes do not provide the desired rule sensitivity. We implemented methods for enhancing commercial drug-drug interaction rules while preserving the original rule base architecture for easy and low cost maintenance.

Original languageEnglish
Pages (from-to)1094
Number of pages1
JournalAMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium
StatePublished - 2005


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