TY - JOUR
T1 - CT Findings after Radiofrequency Ablation in Rabbit Livers
T2 - Comparison of Internally Cooled Electrodes, Perfusion Electrodes, and Internally Cooled Perfusion Electrodes
AU - Kim, Seung Kwon
AU - Gu, Myung Seo
AU - Hong, Hyun Pyo
AU - Choi, Dongil
AU - Chae, Seoung Wan
N1 - Funding Information:
This work was supported by Samsung Biomedical Research Institute grant, SBRI C-A5-208-1.
PY - 2007/11
Y1 - 2007/11
N2 - Purpose: To compare the computed tomography (CT) findings of radiofrequency (RF) ablation of rabbit livers with the use of internally cooled electrodes, perfusion electrodes, and internally cooled perfusion (ICP) electrodes. Materials and Methods: RF ablation zones were created in 24 rabbit livers in vivo in three groups, each treated at 30 W for 30 minutes with an electrode with a 1-cm active portion: one group was treated with an internally cooled electrode (group A), one with a perfusion electrode (group B), and one with an ICP electrode (group C). In the latter two groups, 0.9% saline solution mixed with contrast medium (9:1 ratio) was infused at a rate of 1 mL/min. Immediate CT images were ascertained in all groups and follow-up CT was performed in the latter two groups. CT findings of the RF ablation zone and surrounding liver parenchyma were evaluated and compared among groups. Results: On immediate unenhanced CT, infused contrast medium was noted in the center of the ablation zone without extravasation. Marginal linear or tubular low densities of the RF ablation zone were noted only in groups B (n = 4) and C (n = 3). Liver infarction was more frequently noted in groups B (n = 5) and C (n = 7) than in group A (n = 3). Periportal tracking was noted more frequently in groups B (n = 7) and C (n = 8) than in group A (n = 1). Pericaval or perihepatic tracking was noted only in groups B (n = 3) and C (n = 3). Extensive portal venous gas was noted in one animal in group C. Conclusions: On CT, RF ablation with the perfusion or ICP electrode seemed to show more severe surrounding parenchymal changes than RF ablation with an internally cooled electrode.
AB - Purpose: To compare the computed tomography (CT) findings of radiofrequency (RF) ablation of rabbit livers with the use of internally cooled electrodes, perfusion electrodes, and internally cooled perfusion (ICP) electrodes. Materials and Methods: RF ablation zones were created in 24 rabbit livers in vivo in three groups, each treated at 30 W for 30 minutes with an electrode with a 1-cm active portion: one group was treated with an internally cooled electrode (group A), one with a perfusion electrode (group B), and one with an ICP electrode (group C). In the latter two groups, 0.9% saline solution mixed with contrast medium (9:1 ratio) was infused at a rate of 1 mL/min. Immediate CT images were ascertained in all groups and follow-up CT was performed in the latter two groups. CT findings of the RF ablation zone and surrounding liver parenchyma were evaluated and compared among groups. Results: On immediate unenhanced CT, infused contrast medium was noted in the center of the ablation zone without extravasation. Marginal linear or tubular low densities of the RF ablation zone were noted only in groups B (n = 4) and C (n = 3). Liver infarction was more frequently noted in groups B (n = 5) and C (n = 7) than in group A (n = 3). Periportal tracking was noted more frequently in groups B (n = 7) and C (n = 8) than in group A (n = 1). Pericaval or perihepatic tracking was noted only in groups B (n = 3) and C (n = 3). Extensive portal venous gas was noted in one animal in group C. Conclusions: On CT, RF ablation with the perfusion or ICP electrode seemed to show more severe surrounding parenchymal changes than RF ablation with an internally cooled electrode.
UR - http://www.scopus.com/inward/record.url?scp=35448971503&partnerID=8YFLogxK
U2 - 10.1016/j.jvir.2007.08.010
DO - 10.1016/j.jvir.2007.08.010
M3 - Article
C2 - 18003993
AN - SCOPUS:35448971503
SN - 1051-0443
VL - 18
SP - 1417
EP - 1427
JO - Journal of Vascular and Interventional Radiology
JF - Journal of Vascular and Interventional Radiology
IS - 11
ER -