CSF levels of carnitine in children with meningitis, neurologic disorders, acute gastroenteritis, and seizure

Marwan Shinawi, Nachman Gruener, Aaron Lerner

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Carnitine concentrations in CSF, serum, and urine in normal febrile children and children with meningitis, neurologic disorders, and dehydration were studied. Carnitine levels in CSF were 1/10 compared with serum in normal febrile children. These levels increased two- to threefold in the pathologic conditions studied. Since damage to the blood-brain barrier occurs in these conditions, higher blood-brain barrier permeability might explain CNS carnitine accumulation.

Original languageEnglish
Pages (from-to)1869-1871
Number of pages3
JournalNeurology
Volume50
Issue number6
DOIs
StatePublished - Jun 1998

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