Crystallographic studies of glutamate dehydrogenase. II. Preliminary crystal data for the tuna liver enzyme

Jens J. Birktoft, Fumio Miake, Carl Frieden, Leonard J. Banaszak

Research output: Contribution to journalLetterpeer-review

8 Scopus citations

Abstract

X-ray examination of large crystals of glutamate dehydrogenase prepared from yellowfin tuna liver indicate that the crystals belong to space group I23 (or I213) with a = b = c = 228·4 Å. The unit cell contains 72 subunits (12 hexameric molecules) of molecular weight about 55,500, and there is one half-molecule, i.e. three subunits in the asymmetric unit. The X-ray diffraction data indicate that the crystalline tuna liver glutamate dehydrogenase appears more suitable for structural analysis than the previously obtained crystals of the rat liver enzyme (Birktoft et al., 1979).

Original languageEnglish
Pages (from-to)145-148
Number of pages4
JournalJournal of Molecular Biology
Volume138
Issue number1
DOIs
StatePublished - Mar 25 1980

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