Crystallographic evidence of drastic conformational changes in the active site of a flavin-dependent N -hydroxylase

Keyphrases

• Active Sites 100%
• Conformational Change 100%
• Hydroxylase 100%
• Flavin-dependent 100%
• Biochemical Data 66%
• Hydroxylated 66%
• Kutznerides 66%
• Amino Acids 33%
• Structural Information 33%
• Mechanistic Insight 33%
• NAD(P) 33%
• Spectroscopic Data 33%
• Reaction Mechanism 33%
• Antibiotic Activity 33%
• Natural Products 33%
• Chemical Scaffolds 33%
• Enzyme Class 33%
• Protein Crystals 33%
• Antifungal Properties 33%
• Antimicrobial Properties 33%
• Protein Backbone 33%
• Ornithine 33%
• Flavoenzyme 33%
• Series of Structures 33%
• Flavin Cofactor 33%
• Piperazic Acid 33%
• Soil Actinomycetes 33%
• Nonribosomal Peptide Synthesis 33%

Biochemistry, Genetics and Molecular Biology

• Active Site 100%
• Conformational Change 100%
• Oxygenase 100%
• Antimicrobial Activity 66%
• Enzyme 33%
• Amino Acids 33%
• Antifungal Activity 33%
• Actinobacteria 33%
• Flavoprotein 33%
• Ornithine 33%
• Nonribosomal Peptide Synthesis 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Oxygenase 100%
• Riboflavin Derivative 100%
• Amino Acid 33%
• Antiinfective Agent 33%
• Natural Product 33%
• Actinobacteria 33%
• Ornithine 33%
• Flavoprotein 33%
• Antimicrobial Agent 33%