Crohn's Disease Is Associated With an Increased Prevalence of Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study Using Magnetic Resonance Proton Density Fat Fraction Mapping

Scott McHenry; Yeshika Sharma; Ankita Tirath; Richard Tsai; Aaron Mintz; Tyler J. Fraum; Amber Salter; Jeffrey D. Browning; Avegail G. Flores; Nicholas O. Davidson; Kathryn J. Fowler; Matthew A. Ciorba; Parakkal Deepak

doi:10.1016/j.cgh.2019.02.045

Crohn's Disease Is Associated With an Increased Prevalence of Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study Using Magnetic Resonance Proton Density Fat Fraction Mapping

Scott McHenry, Yeshika Sharma, Ankita Tirath, Richard Tsai, Aaron Mintz, Tyler J. Fraum, Amber Salter, Jeffrey D. Browning, Avegail G. Flores, Nicholas O. Davidson, Kathryn J. Fowler, Matthew A. Ciorba, Parakkal Deepak

Research output: Contribution to journal › Short survey › peer-review

17 Scopus citations

Abstract

Nonalcoholic fatty liver disease (NAFLD) commonly coexists with Crohn's disease (CD); however, it remains unclear if it is more prevalent than would be expected as ultrasound surveys of CD patients report a very wide range of prevalence (9%–40%).^1–3 To address this uncertainty, we performed a prospective, cross-sectional survey of NAFLD in CD patients by generating magnetic resonance proton density fat fraction (MR-PDFF) maps as compared with 2 control populations. MR-PDFF provides a quantitative, sensitive and specific (97% and 100%, respectively) radiographic surrogate for liver fat.⁴

Original language	English
Pages (from-to)	2816-2818
Number of pages	3
Journal	Clinical Gastroenterology and Hepatology
Volume	17
Issue number	13
DOIs	https://doi.org/10.1016/j.cgh.2019.02.045
State	Published - Dec 2019

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McHenry, S., Sharma, Y., Tirath, A., Tsai, R., Mintz, A., Fraum, T. J., Salter, A., Browning, J. D., Flores, A. G., Davidson, N. O., Fowler, K. J., Ciorba, M. A., & Deepak, P. (2019). Crohn's Disease Is Associated With an Increased Prevalence of Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study Using Magnetic Resonance Proton Density Fat Fraction Mapping. Clinical Gastroenterology and Hepatology, 17(13), 2816-2818. https://doi.org/10.1016/j.cgh.2019.02.045

@article{8494bbe7eeaa42e9bbf2cf28446aee59,

title = "Crohn's Disease Is Associated With an Increased Prevalence of Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study Using Magnetic Resonance Proton Density Fat Fraction Mapping",

abstract = "Nonalcoholic fatty liver disease (NAFLD) commonly coexists with Crohn's disease (CD); however, it remains unclear if it is more prevalent than would be expected as ultrasound surveys of CD patients report a very wide range of prevalence (9%–40%).1–3 To address this uncertainty, we performed a prospective, cross-sectional survey of NAFLD in CD patients by generating magnetic resonance proton density fat fraction (MR-PDFF) maps as compared with 2 control populations. MR-PDFF provides a quantitative, sensitive and specific (97% and 100%, respectively) radiographic surrogate for liver fat.4",

author = "Scott McHenry and Yeshika Sharma and Ankita Tirath and Richard Tsai and Aaron Mintz and Fraum, {Tyler J.} and Amber Salter and Browning, {Jeffrey D.} and Flores, {Avegail G.} and Davidson, {Nicholas O.} and Fowler, {Kathryn J.} and Ciorba, {Matthew A.} and Parakkal Deepak",

note = "Publisher Copyright: {\textcopyright} 2019 AGA Institute",

year = "2019",

month = dec,

doi = "10.1016/j.cgh.2019.02.045",

language = "English",

volume = "17",

pages = "2816--2818",

journal = "Clinical Gastroenterology and Hepatology",

issn = "1542-3565",

number = "13",

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McHenry, S, Sharma, Y, Tirath, A, Tsai, R , Mintz, A , Fraum, TJ, Salter, A, Browning, JD, Flores, AG, Davidson, NO, Fowler, KJ, Ciorba, MA & Deepak, P 2019, 'Crohn's Disease Is Associated With an Increased Prevalence of Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study Using Magnetic Resonance Proton Density Fat Fraction Mapping', Clinical Gastroenterology and Hepatology, vol. 17, no. 13, pp. 2816-2818. https://doi.org/10.1016/j.cgh.2019.02.045

Crohn's Disease Is Associated With an Increased Prevalence of Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study Using Magnetic Resonance Proton Density Fat Fraction Mapping. / McHenry, Scott; Sharma, Yeshika; Tirath, Ankita et al.
In: Clinical Gastroenterology and Hepatology, Vol. 17, No. 13, 12.2019, p. 2816-2818.

Research output: Contribution to journal › Short survey › peer-review

TY - JOUR

T1 - Crohn's Disease Is Associated With an Increased Prevalence of Nonalcoholic Fatty Liver Disease

T2 - A Cross-Sectional Study Using Magnetic Resonance Proton Density Fat Fraction Mapping

AU - McHenry, Scott

AU - Sharma, Yeshika

AU - Tirath, Ankita

AU - Tsai, Richard

AU - Mintz, Aaron

AU - Fraum, Tyler J.

AU - Salter, Amber

AU - Browning, Jeffrey D.

AU - Flores, Avegail G.

AU - Davidson, Nicholas O.

AU - Fowler, Kathryn J.

AU - Ciorba, Matthew A.

AU - Deepak, Parakkal

PY - 2019/12

Y1 - 2019/12

N2 - Nonalcoholic fatty liver disease (NAFLD) commonly coexists with Crohn's disease (CD); however, it remains unclear if it is more prevalent than would be expected as ultrasound surveys of CD patients report a very wide range of prevalence (9%–40%).1–3 To address this uncertainty, we performed a prospective, cross-sectional survey of NAFLD in CD patients by generating magnetic resonance proton density fat fraction (MR-PDFF) maps as compared with 2 control populations. MR-PDFF provides a quantitative, sensitive and specific (97% and 100%, respectively) radiographic surrogate for liver fat.4

AB - Nonalcoholic fatty liver disease (NAFLD) commonly coexists with Crohn's disease (CD); however, it remains unclear if it is more prevalent than would be expected as ultrasound surveys of CD patients report a very wide range of prevalence (9%–40%).1–3 To address this uncertainty, we performed a prospective, cross-sectional survey of NAFLD in CD patients by generating magnetic resonance proton density fat fraction (MR-PDFF) maps as compared with 2 control populations. MR-PDFF provides a quantitative, sensitive and specific (97% and 100%, respectively) radiographic surrogate for liver fat.4

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U2 - 10.1016/j.cgh.2019.02.045

DO - 10.1016/j.cgh.2019.02.045

M3 - Short survey

C2 - 30876963

AN - SCOPUS:85065246220

SN - 1542-3565

VL - 17

SP - 2816

EP - 2818

JO - Clinical Gastroenterology and Hepatology

JF - Clinical Gastroenterology and Hepatology

IS - 13

ER -

Crohn's Disease Is Associated With an Increased Prevalence of Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study Using Magnetic Resonance Proton Density Fat Fraction Mapping

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