Criteria for the standardization of stem-cell-based embryo models

Alfonso Martinez Arias, Nicolas Rivron, Naomi Moris, Patrick Tam, Cantas Alev, Jianping Fu, Anna Katerina Hadjantonakis, Jacob H. Hanna, Gabriella Minchiotti, Olivier Pourquie, Guojun Sheng, Liliana Solnica Krezel, Jesse V. Veenvliet, Aryeh Warmflash

Research output: Contribution to journalComment/debate

2 Scopus citations

Abstract

Pluripotent stem cells are being used to generate models of early embryogenesis that are promising for discovery and translational research. To be useful, these models require critical consideration of their level of efficiency and fidelity to natural embryos. Here we propose criteria with which to raise the standards of stem-cell-based embryo models of human embryogenesis.

Original languageEnglish
Pages (from-to)1625-1628
Number of pages4
JournalNature Cell Biology
Volume26
Issue number10
DOIs
StatePublished - Oct 2024

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