TY - JOUR
T1 - Creutzfeldt-Jakob disease with extensive degeneration of white matter
AU - Park, Tae Sung
AU - Kleinman, George M.
AU - Richardson, Edward P.
PY - 1980/1
Y1 - 1980/1
N2 - Degeneration of the white matter is uncommon in Creutzfeldt-Jakob disease (CJD), and when it occurs is usually mild, and limited in distribution. In the case of a 77-year-old woman with CJD lasting 1 year, there was extensive degeneration of cerebral white matter in addition to severe loss of neurons and hypertrophic astrogliosis in cortex and striatum. The extent and severity of white matter lesions makes the case unusual.
AB - Degeneration of the white matter is uncommon in Creutzfeldt-Jakob disease (CJD), and when it occurs is usually mild, and limited in distribution. In the case of a 77-year-old woman with CJD lasting 1 year, there was extensive degeneration of cerebral white matter in addition to severe loss of neurons and hypertrophic astrogliosis in cortex and striatum. The extent and severity of white matter lesions makes the case unusual.
KW - Creutzfeldt-Jakob disease
KW - Spongiform encephalopathy
KW - White-matter degeneration
UR - http://www.scopus.com/inward/record.url?scp=0019175731&partnerID=8YFLogxK
U2 - 10.1007/BF00705813
DO - 10.1007/BF00705813
M3 - Article
C2 - 7004049
AN - SCOPUS:0019175731
SN - 0001-6322
VL - 52
SP - 239
EP - 242
JO - Acta Neuropathologica
JF - Acta Neuropathologica
IS - 3
ER -