Cortical folding is altered before surgery in infants with congenital heart disease

Cynthia Ortinau; Dimitrios Alexopoulos; Donna Dierker; David Van Essen; John Beca; Terrie Inder

doi:10.1016/j.jpeds.2013.06.045

Cortical folding is altered before surgery in infants with congenital heart disease

Cynthia Ortinau
, Dimitrios Alexopoulos
, Donna Dierker
, David Van Essen
, John Beca
, Terrie Inder

Research output: Contribution to journal › Article › peer-review

65 Scopus citations

Abstract

Infants with congenital heart disease have altered brain development. We characterized cortical folding, a critical part of brain development, in congenital heart disease infants and demonstrated an overall decrease in cortical surface area and cortical folding with regional alterations in the right lateral sulcus and left orbitofrontal region, cingulate region, and central sulcus. These abnormalities were present prior to surgery.

Original language	English
Pages (from-to)	1507-1510
Number of pages	4
Journal	Journal of Pediatrics
Volume	163
Issue number	5
DOIs	https://doi.org/10.1016/j.jpeds.2013.06.045
State	Published - Nov 2013

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10.1016/j.jpeds.2013.06.045

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@article{42d4cfa0bad84fe49c2ce7b1ec88a0f4,

title = "Cortical folding is altered before surgery in infants with congenital heart disease",

abstract = "Infants with congenital heart disease have altered brain development. We characterized cortical folding, a critical part of brain development, in congenital heart disease infants and demonstrated an overall decrease in cortical surface area and cortical folding with regional alterations in the right lateral sulcus and left orbitofrontal region, cingulate region, and central sulcus. These abnormalities were present prior to surgery.",

author = "Cynthia Ortinau and Dimitrios Alexopoulos and Donna Dierker and \{Van Essen\}, David and John Beca and Terrie Inder",

year = "2013",

month = nov,

doi = "10.1016/j.jpeds.2013.06.045",

language = "English",

volume = "163",

pages = "1507--1510",

journal = "Journal of Pediatrics",

issn = "0022-3476",

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T1 - Cortical folding is altered before surgery in infants with congenital heart disease

AU - Ortinau, Cynthia

AU - Alexopoulos, Dimitrios

AU - Dierker, Donna

AU - Van Essen, David

AU - Beca, John

AU - Inder, Terrie

PY - 2013/11

Y1 - 2013/11

N2 - Infants with congenital heart disease have altered brain development. We characterized cortical folding, a critical part of brain development, in congenital heart disease infants and demonstrated an overall decrease in cortical surface area and cortical folding with regional alterations in the right lateral sulcus and left orbitofrontal region, cingulate region, and central sulcus. These abnormalities were present prior to surgery.

AB - Infants with congenital heart disease have altered brain development. We characterized cortical folding, a critical part of brain development, in congenital heart disease infants and demonstrated an overall decrease in cortical surface area and cortical folding with regional alterations in the right lateral sulcus and left orbitofrontal region, cingulate region, and central sulcus. These abnormalities were present prior to surgery.

UR - https://www.scopus.com/pages/publications/84886693401

U2 - 10.1016/j.jpeds.2013.06.045

DO - 10.1016/j.jpeds.2013.06.045

M3 - Article

C2 - 23988135

AN - SCOPUS:84886693401

SN - 0022-3476

VL - 163

SP - 1507

EP - 1510

JO - Journal of Pediatrics

JF - Journal of Pediatrics

IS - 5

ER -

Cortical folding is altered before surgery in infants with congenital heart disease

Abstract

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