TY - JOUR
T1 - Cortical folding is altered before surgery in infants with congenital heart disease
AU - Ortinau, Cynthia
AU - Alexopoulos, Dimitrios
AU - Dierker, Donna
AU - Van Essen, David
AU - Beca, John
AU - Inder, Terrie
PY - 2013/11
Y1 - 2013/11
N2 - Infants with congenital heart disease have altered brain development. We characterized cortical folding, a critical part of brain development, in congenital heart disease infants and demonstrated an overall decrease in cortical surface area and cortical folding with regional alterations in the right lateral sulcus and left orbitofrontal region, cingulate region, and central sulcus. These abnormalities were present prior to surgery.
AB - Infants with congenital heart disease have altered brain development. We characterized cortical folding, a critical part of brain development, in congenital heart disease infants and demonstrated an overall decrease in cortical surface area and cortical folding with regional alterations in the right lateral sulcus and left orbitofrontal region, cingulate region, and central sulcus. These abnormalities were present prior to surgery.
UR - http://www.scopus.com/inward/record.url?scp=84886693401&partnerID=8YFLogxK
U2 - 10.1016/j.jpeds.2013.06.045
DO - 10.1016/j.jpeds.2013.06.045
M3 - Article
C2 - 23988135
AN - SCOPUS:84886693401
SN - 0022-3476
VL - 163
SP - 1507
EP - 1510
JO - Journal of Pediatrics
JF - Journal of Pediatrics
IS - 5
ER -