Correlative Imaging in Neuroendocrine Tumors

Ameya Puranik; Sonal Prasad; Indraja D. Devi; Vikas Prasad

doi:10.1002/9781119603627.ch17

Correlative Imaging in Neuroendocrine Tumors

Ameya Puranik, Sonal Prasad, Indraja D. Devi, Vikas Prasad

Division of Nuclear Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Neuroendocrine tumors (NETs) are a large group of heterogeneous tumors arising from enterochromaffin cells of neural crest origin. NETs are broadly classified as functional and nonfunctional as many of these tumors have an ability to produce and secrete peptide hormones and biogenic amines, which in turn are responsible for their clinical manifestations. As NETs are hypervascular tumors, they are intensely enhanced on contrast-enhanced computed tomography (CT) scans. Magnetic resonance imaging has better sensitivity than conventional contrast-enhanced CT in the evaluation of liver metastases from NETs. Functional imaging utilizes various compounds tagged with another radioactive compound, which emits radiation, in turn captured by either a gamma camera or a positron emission tomography (PET) machine. Radiopharmaceuticals are indispensable tools for molecular imaging of NETs. The role of ¹⁸F-DOPA PET in the staging of well differentiated grade 1 and grade 2 NET is limited.

Original language	English
Title of host publication	Radiology-Nuclear Medicine Diagnostic Imaging
Subtitle of host publication	A Correlative Approach
Publisher	wiley
Pages	512-520
Number of pages	9
ISBN (Electronic)	9781119603627
ISBN (Print)	9781119603610
DOIs	https://doi.org/10.1002/9781119603627.ch17
State	Published - Jan 1 2023

Keywords

Computed tomography
Functional imaging
Gamma camera
Hypervascular tumors
Magnetic resonance imaging
Neuroendocrine tumors
Positron emission tomography
Radiopharmaceuticals

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10.1002/9781119603627.ch17

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abstract = "Neuroendocrine tumors (NETs) are a large group of heterogeneous tumors arising from enterochromaffin cells of neural crest origin. NETs are broadly classified as functional and nonfunctional as many of these tumors have an ability to produce and secrete peptide hormones and biogenic amines, which in turn are responsible for their clinical manifestations. As NETs are hypervascular tumors, they are intensely enhanced on contrast-enhanced computed tomography (CT) scans. Magnetic resonance imaging has better sensitivity than conventional contrast-enhanced CT in the evaluation of liver metastases from NETs. Functional imaging utilizes various compounds tagged with another radioactive compound, which emits radiation, in turn captured by either a gamma camera or a positron emission tomography (PET) machine. Radiopharmaceuticals are indispensable tools for molecular imaging of NETs. The role of 18F-DOPA PET in the staging of well differentiated grade 1 and grade 2 NET is limited.",

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author = "Ameya Puranik and Sonal Prasad and Devi, {Indraja D.} and Vikas Prasad",

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AU - Prasad, Sonal

AU - Devi, Indraja D.

AU - Prasad, Vikas

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N2 - Neuroendocrine tumors (NETs) are a large group of heterogeneous tumors arising from enterochromaffin cells of neural crest origin. NETs are broadly classified as functional and nonfunctional as many of these tumors have an ability to produce and secrete peptide hormones and biogenic amines, which in turn are responsible for their clinical manifestations. As NETs are hypervascular tumors, they are intensely enhanced on contrast-enhanced computed tomography (CT) scans. Magnetic resonance imaging has better sensitivity than conventional contrast-enhanced CT in the evaluation of liver metastases from NETs. Functional imaging utilizes various compounds tagged with another radioactive compound, which emits radiation, in turn captured by either a gamma camera or a positron emission tomography (PET) machine. Radiopharmaceuticals are indispensable tools for molecular imaging of NETs. The role of 18F-DOPA PET in the staging of well differentiated grade 1 and grade 2 NET is limited.

AB - Neuroendocrine tumors (NETs) are a large group of heterogeneous tumors arising from enterochromaffin cells of neural crest origin. NETs are broadly classified as functional and nonfunctional as many of these tumors have an ability to produce and secrete peptide hormones and biogenic amines, which in turn are responsible for their clinical manifestations. As NETs are hypervascular tumors, they are intensely enhanced on contrast-enhanced computed tomography (CT) scans. Magnetic resonance imaging has better sensitivity than conventional contrast-enhanced CT in the evaluation of liver metastases from NETs. Functional imaging utilizes various compounds tagged with another radioactive compound, which emits radiation, in turn captured by either a gamma camera or a positron emission tomography (PET) machine. Radiopharmaceuticals are indispensable tools for molecular imaging of NETs. The role of 18F-DOPA PET in the staging of well differentiated grade 1 and grade 2 NET is limited.

KW - Computed tomography

KW - Functional imaging

KW - Gamma camera

KW - Hypervascular tumors

KW - Magnetic resonance imaging

KW - Neuroendocrine tumors

KW - Positron emission tomography

KW - Radiopharmaceuticals

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BT - Radiology-Nuclear Medicine Diagnostic Imaging

PB - wiley

ER -

Correlative Imaging in Neuroendocrine Tumors

Abstract

Keywords

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