Correlation of LUMO localization with the α-amylase inhibition constant in a Tendamistat-based series of linear and cyclic peptides

Keyphrases

• Linear Peptide 100%
• Cyclic Peptide 100%
• Orbital Localization 100%
• Tendamistat 100%
• Lowest Unoccupied Molecular Orbital 100%
• Inhibition Constant 100%
• α-amylase Inhibition 100%
• α-amylase 66%
• Small Intestine 33%
• Blood Glucose 33%
• Disease States 33%
• Glycosidase 33%
• Enzyme Activity 33%
• Proteinase Inhibitor 33%
• Small Peptides 33%
• Positive Charge 33%
• Blood Sugar 33%
• Triplet 33%
• Peptide-based 33%
• Glycosidic Linkage 33%
• Active Molecules 33%
• Glucose Absorption 33%
• Dietary Starch 33%
• Molecular-level Interaction 33%
• Predictive Model 33%
• Diabetes Mellitus 33%
• Natural Protein 33%
• Active Inhibitor 33%

Biochemistry, Genetics and Molecular Biology

• Cyclic Peptide 100%
• Koji 100%
• Glucose Blood Level 66%
• Enzymatic Hydrolysis 33%
• Conformation 33%
• Glycoside Hydrolase 33%
• Enzyme Activity 33%
• Small Intestine 33%
• Starch 33%
• Glycosidic Linkage 33%
• Glucose Absorption 33%
• Arginine 33%
• Peptide 33%