Corrections for Accidental Coincidences and Attenuation in Maximum-Likelihood Image Reconstruction for Positron-Emission Tomography

David G. Politte, Donald L. Snyder

Research output: Contribution to journalArticle

114 Scopus citations

Abstract

A new method has been developed and tested for correcting for the effects of accidental coincidences and photon attenuation in positron-emission tomography. A mathematical model is used for these effects as the basis for the development. The corrections are incorporated into the iterations of an expectation-maximization algorithm for numerically producing the maximum-likelihood estimate of a distribution of radioactivity within a patient. We have found the images reconstructed with this new procedure to be unbiased and to exhibit lower variance than those reconstructed from precorrected data.

Original languageEnglish
Pages (from-to)82-89
Number of pages8
JournalIEEE Transactions on Medical Imaging
Volume10
Issue number1
DOIs
StatePublished - Mar 1991

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