Correction: The heme oxygenase 1 inducer (CoPP) protects human cardiac stem cells against apoptosis through activation of the extracellular signal-related kinase (ERK)/NRF2 signaling pathway and cytokine release (Journal of Biological Chemistry (2012) 287:40 (33720-33732) DOI:10.1074/jbc.M112.385542)

Chuanxi Cai, Lei Teng, Duc Vu, Jia Qiang He, Yiru Guo, Qianghong Li, Xian Liang Tang, Gregg Rokosh, Aruni Bhatnagar, Roberto Bolli

Research output: Contribution to journalComment/debate

Abstract

The wrong tubulin immunoblot was used in Fig. 1E. The wrong FACS plot image was used in the lower right panel of Fig. 5C. The wrong t-ERK and tubulin immunoblots were used in Fig. 7C. In supplemental Fig. S2B, the wrong tubulin immunoblot was used. Additionally, the wrong number (n 4) of independent experiments was used for the FACS analyses shown in Figs. 2, B and C, 3, C and D, 4, C and D, and 5, C and D. The FACS analyses for cell apoptosis assays were performed at the same time for hCSCs expressing scramble shRNA (Fig. 2, B and C), HO-1 shRNA (Fig. 3, C and D), NRF2 shRNA (Fig. 4, C and D), or COX-2 shRNA (Fig. 5, C and D). For all groups of cells, there were 8 independent experiments except hCSCs expressing scramble shRNA with CoPP preconditioning but not subjected to oxidative stress, for which there were 7 independent experiments (due to insufficient cell numbers). These 8 or 7 original data sets were reanalyzed and corrected with the new quantitative data. Representative images for the FACS plots were selected from 1 of the 8 experiments. These errors have now been corrected and do not affect the results or conclusions of this work.

Original languageEnglish
Pages (from-to)4725-4727
Number of pages3
JournalJournal of Biological Chemistry
Volume294
Issue number12
DOIs
StatePublished - Mar 22 2019

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