Coping and quality of life in patients awaiting lung transplantation

Jessica L. Taylor, Patrick J. Smith, Michael A. Babyak, Krista A. Barbour, Benson M. Hoffman, Deborah L. Sebring, R. Duane Davis, Scott M. Palmer, Francis J. Keefe, Robert M. Carney, Iris Csik, Kenneth E. Freedland, James A. Blumenthal

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


Objective: Patients with end-stage lung disease (ESLD) experience significant decrements in quality of life (QOL). Although coping strategies are related to QOL in patients with ESLD, the extent to which specific native lung disease moderates this relationship is unknown. Methods: We investigated the relationship between coping, native lung disease, and QOL among 187 patients awaiting lung transplantation, including 139 patients with chronic obstructive pulmonary disease (COPD) and 48 with cystic fibrosis (CF). Participants completed a psychosocial battery assessing psychological QOL, physical QOL, and coping strategies. Results: For both COPD and CF patients, higher levels of Active Coping (P<.0001) and lower levels of Disengagement (P<.0001) were associated with better psychological QOL. For physical QOL, we observed a Native Disease×Coping interaction (P=.01) such that Active Coping was associated with better physical QOL in patients with COPD but not in patients with CF. Conclusions: The relationship between coping and QOL may vary as a function of native lung disease. Patients' native disease may need to be considered in order to develop effective interventions to help patients cope successfully with ESLD.

Original languageEnglish
Pages (from-to)71-79
Number of pages9
JournalJournal of Psychosomatic Research
Issue number1
StatePublished - Jul 2008


  • Chronic obstructive pulmonary disease
  • Coping
  • Cystic fibrosis
  • Lung transplant
  • Quality of life


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