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Conversion of human and mouse fibroblasts into lung-like epithelial cells
Amy P. Wong
, Sharareh Shojaie
, Qin Liang
, Sunny Xia
, Michelle Di Paola
,
Saumel Ahmadi
, Claudia Bilodeau
, Jodi Garner
, Martin Post
, Pascal Duchesneau
, Thomas K. Waddell
, Christine E. Bear
, Andras Nagy
, Janet Rossant
Section of Pediatric Epilepsy
Institute of Clinical and Translational Sciences (ICTS)
Research output
:
Contribution to journal
›
Article
›
peer-review
10
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Scopus citations
Overview
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Keyphrases
Lung
100%
Human Fibroblasts
100%
Epithelial Cells
100%
Mouse Embryonic Fibroblasts
100%
Fibroblasts
33%
KLF4
16%
Sex-determining Region Y-box 2 (SOX2)
16%
C-Myc
16%
Reprogramming Factors
16%
Octamer-binding Transcription Factor 4 (OCT4)
16%
Transcription Factor
16%
Transplantation
16%
Dermal Fibroblasts
16%
Rat Lung
16%
Regenerative Medicine
16%
Lung Scaffold
16%
Cell Lineage
16%
Cystic Fibrosis
16%
Directed Differentiation
16%
Patient-specific
16%
Lung Function
16%
Ciliated Cells
16%
Regeneration Strategy
16%
Transdifferentiation
16%
Goblet Cells
16%
Specialized Cell
16%
Basal Cell
16%
Human-induced
16%
Nkx2.1
16%
Cell Source
16%
Human Adult
16%
Pharmacological Rescue
16%
CFTR Function
16%
Lung Epithelium
16%
Air-liquid Interface Culture
16%
Club Cells
16%
Immune-compromised
16%
Ivacaftor
16%
Lumacaftor
16%
Decellularized
16%
ΔF508
16%
Lineage Conversion
16%
Lung Cell Types
16%
Medicine and Dentistry
Epithelial Cell
100%
Lung
100%
Fibroblast
100%
Medicine
11%
Cystic Fibrosis
11%
Transcription Factors
11%
Cell Lineage
11%
Cell Transdifferentiation
11%
Oncogene C Myc
11%
Lung Epithelium
11%
Ivacaftor
11%
Lumacaftor
11%
Diseases
11%
Biochemistry, Genetics and Molecular Biology
Fibroblast
100%
Reprogramming
25%
Oncogene C Myc
25%
Transcription Factors
25%
Cell Lineage
25%
Cystic Fibrosis
25%
Directed Differentiation
25%
Goblet Cell
25%
Transdifferentiation
25%
Club Cell
25%
Ivacaftor
25%
Lumacaftor
25%