Conventional Surgical Treatment of Hepatocellular Carcinoma

T. Mark Earl, William C. Chapman

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations


Liver resection remains the standard therapy for solitary hepatocellular carcinoma in patients with preserved hepatic function. In well-selected patients, 5-year survival rates are good and can approach that of liver transplantation for early-stage disease. Patient selection is critical to optimizing therapeutic benefit, and the health of the native liver must be considered in addition to tumor characteristics. Hepatic recurrence after resection is common. The difficulty lies in deciding which patients with chronic liver disease and small solitary tumors are best served by resection and which should proceed with transplant evaluation; this is the focus of this article.

Original languageEnglish
Pages (from-to)353-370
Number of pages18
JournalClinics in Liver Disease
Issue number2
StatePublished - May 2011


  • Cirrhosis
  • Hepatocellular carcinoma
  • Liver cancer
  • Surgical resection


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