Control Theory for Closed-Loop Neurophysiology

G. Kumar, J. T. Ritt, S. Ching

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations


This chapter presents an overview of emerging research problems at the boundary between control engineering and neuroscience, toward implementation of closed-loop paradigms for modulating brain activity. Emphasis will be placed on both recent theoretical developments-eg, system identification and controllability in neuronal networks-and real-world constraints in applications such as clinical deep brain stimulation, or optical stimulation in experimental neuroscience. Discussion will extend to how these constraints may necessitate the development of entirely new paradigms in systems and control theory that respond to the unprecedented challenges facing neuroscientists and neural engineers.

Original languageEnglish
Title of host publicationClosed Loop Neuroscience
PublisherElsevier Inc.
Number of pages18
ISBN (Electronic)9780128026410
ISBN (Print)9780128024522
StatePublished - Sep 29 2016


  • Closed-loop neurophysiology
  • Deep brain stimulation
  • Dynamical systems models
  • Hodgkin-Huxley model
  • Neural control
  • Neurostimulation


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