Keyphrases
Channel Gating
100%
Cytoplasmic Domain
100%
Kir Channels
100%
Domain Interface
100%
Interface Interaction
100%
Kir6.2
80%
Channel Activity
80%
Salt Bridge
80%
Phosphatidylinositol 4,5-bisphosphate (PIP2)
40%
Inactivation Mechanism
40%
Kir2.1 Channel
40%
Potassium
20%
Gain-of-function mutation
20%
Insulin Secretion
20%
KATP Channel
20%
SUR1
20%
Excitability
20%
Re-exposure
20%
Disease-causing mutations
20%
Inward Rectifier Potassium Channel
20%
Kir2.1
20%
Kinetic Model
20%
Membrane Excitability
20%
Congenital Hyperinsulinism
20%
Major Determinants
20%
Cellular Metabolism
20%
Pore-forming
20%
Domain-domain Interaction
20%
Mammalian Tissue
20%
Kir6.2 Channel
20%
PIP2 Binding
20%
Neuroscience
Adenosine Triphosphate
100%
Channel Gating
100%
Kir6.2
75%
Excitability
50%
Inwardly Rectifying Potassium Channel Subunit Kir6.2
50%
Inwardly Rectifying Potassium Channel Subunit Kir2.1
50%
Metabolic Pathway
25%
Phosphatidylinositol 4,5-bisphosphate
25%
Sulfonylurea Receptor
25%
Behavior (Neuroscience)
25%
Face
25%
Adenosine Triphosphate Sensitive Potassium Channel
25%
Inward-Rectifier Potassium Ion Channel
25%
Loss of Function Mutation
25%
Kir2.1
25%
Congenital Hyperinsulinism
25%
Biochemistry, Genetics and Molecular Biology
Channel Gating
100%
Kir6.2
100%
Adenosine Triphosphate
80%
Kir2.1
60%
Excitability
40%
Phosphatidylinositol 4,5-bisphosphate
20%
Loss of Function Mutation
20%
Sulfonylurea Receptor
20%
Insulin Release
20%
Kinetics
20%
ATP-Sensitive Potassium Channel
20%
Inward-Rectifier Potassium Ion Channel
20%
Cell Metabolism
20%
Congenital Hyperinsulinism
20%
Immunology and Microbiology
Excitability
100%
Channel Gating
100%
Loss of Function Mutation
50%
Face
50%
Insulin Release
50%
ATP-Sensitive Potassium Channel
50%
Cell Metabolism
50%
Kinetics
50%
Inward-Rectifier Potassium Ion Channel
50%
Pharmacology, Toxicology and Pharmaceutical Science
Adenosine Triphosphate
100%
Sodium Chloride
100%
Inwardly Rectifying Potassium Channel Subunit Kir2.1
50%
Inwardly Rectifying Potassium Channel Subunit Kir6.2
50%
Disease
25%
Sulfonylurea Receptor
25%
Isotopes of Potassium
25%
Adenosine Triphosphate Sensitive Potassium Channel
25%
Phosphatidylinositol 4,5 Bisphosphate
25%
Persistent Hyperinsulinemic Hypoglycemia of Infancy
25%