Control of bithorax complex functions by the segmentation gene fushi tarazu of D. melanogaster

Ian Duncan

Research output: Contribution to journalArticlepeer-review

47 Scopus citations

Abstract

The properties of three dominant alleles of ftz are described. These alleles cause transformations of the first abdominal segment to the third and cause alternate segment pattern deletions that are out of phase with respect to those caused by ftz null alleles. To explain the effects of these mutations, a model is proposed in which ftz+ has two roles: to subdivide the body into parasegments and to activate appropriate bithorax complex functions in alternate parasegments. According to this model, the effects of the novel ftz alleles can be understood as arising from a slight widening of the blastoderm stripes of ftz expression.

Original languageEnglish
Pages (from-to)297-309
Number of pages13
JournalCell
Volume47
Issue number2
DOIs
StatePublished - Oct 24 1986

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