Abstract
The Rgg family of transcription regulators is widely distributed among gram-positive bacteria, yet how these proteins control transcription is poorly understood. Using Streptococcus pyogenes RopB as a model, we demonstrated that residues invariant among Rgg-like regulators are critical for function and obtained evidence for a mechanism involving protein complex formation.
Original language | English |
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Pages (from-to) | 650-655 |
Number of pages | 6 |
Journal | Journal of bacteriology |
Volume | 189 |
Issue number | 2 |
DOIs | |
State | Published - Jan 2007 |