Abstract

Human circulating monocytes in tissue culture are capable of resorbing devitalized adult and fetal bone. An important component of this process is the adhesion of the cells to the mineralized substrate and the localized removal of matrix from beneath the attached cells. The process appears to involve both release of lysosomal enzymes onto the substrate and intracellular accumulation (transport) of resorbed matrix.

Original languageEnglish
Pages (from-to)988-990
Number of pages3
JournalScience
Volume199
Issue number4332
DOIs
StatePublished - 1978

Fingerprint

Dive into the research topics of 'Contact-mediated bone resorption by human monocytes in vitro'. Together they form a unique fingerprint.

Cite this