Contact focusing multimodal microprobes for ultraprecise laser tissue surgery

Arash Darafsheh; Amir Fardad; Nathaniel M. Fried; Andrew N. Antoszyk; Howard S. Ying; Vasily N. Astratov

doi:10.1364/OE.19.003440

Contact focusing multimodal microprobes for ultraprecise laser tissue surgery

Arash Darafsheh, Amir Fardad, Nathaniel M. Fried, Andrew N. Antoszyk, Howard S. Ying, Vasily N. Astratov

Research output: Contribution to journal › Article › peer-review

68 Scopus citations

Abstract

Focusing of multimodal beams by chains of dielectric microspheres assembled directly inside the cores of hollow waveguides is studied by using numerical ray tracing. The device designs are optimized for laser surgery in contact mode with strongly absorbing tissue. By analyzing a broad range of parameters it is demonstrated that chains formed by three or five spheres with a refractive index of 1.65-1.75 provide a twofold improvement in spatial resolution over single spheres at the cost of 0.2-0.4 attenuation in peak intensity of the central focused beam. Potential applications include ultra precise laser ablation or coagulation in the eye and brain, cellular surgery, and the coupling of light into photonic nanostructures.

Original language	English
Pages (from-to)	3440-3448
Number of pages	9
Journal	Optics Express
Volume	19
Issue number	4
DOIs	https://doi.org/10.1364/OE.19.003440
State	Published - Feb 14 2011

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abstract = "Focusing of multimodal beams by chains of dielectric microspheres assembled directly inside the cores of hollow waveguides is studied by using numerical ray tracing. The device designs are optimized for laser surgery in contact mode with strongly absorbing tissue. By analyzing a broad range of parameters it is demonstrated that chains formed by three or five spheres with a refractive index of 1.65-1.75 provide a twofold improvement in spatial resolution over single spheres at the cost of 0.2-0.4 attenuation in peak intensity of the central focused beam. Potential applications include ultra precise laser ablation or coagulation in the eye and brain, cellular surgery, and the coupling of light into photonic nanostructures.",

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AU - Fardad, Amir

AU - Fried, Nathaniel M.

AU - Antoszyk, Andrew N.

AU - Ying, Howard S.

AU - Astratov, Vasily N.

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AB - Focusing of multimodal beams by chains of dielectric microspheres assembled directly inside the cores of hollow waveguides is studied by using numerical ray tracing. The device designs are optimized for laser surgery in contact mode with strongly absorbing tissue. By analyzing a broad range of parameters it is demonstrated that chains formed by three or five spheres with a refractive index of 1.65-1.75 provide a twofold improvement in spatial resolution over single spheres at the cost of 0.2-0.4 attenuation in peak intensity of the central focused beam. Potential applications include ultra precise laser ablation or coagulation in the eye and brain, cellular surgery, and the coupling of light into photonic nanostructures.

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Contact focusing multimodal microprobes for ultraprecise laser tissue surgery

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