@article{a2c67d6858d54084b8177019b6465dc2,
title = "Constrained peptidomimetics: Building bicyclic analogs of pyrazoline derivatives",
abstract = "A synthetic route has been developed for incorporating pyrazoline derivatives as proline surrogates in constrained X-Pro peptidomimetics. The route allows for the synthesis of dipeptide building blocks having either a six or seven-membered-ring annulated onto the pyrazoline moiety, as well as for the asymmetric synthesis of analogs having substituents on N-terminal side of the building block.",
keywords = "Bicyclic analogs, Proline surrogates, Pyrazoline",
author = "Bin Liu and Brandt, \{John D.\} and Moeller, \{Kevin D.\}",
note = "Funding Information: We thank the National Science Foundation (CHE-9023698) for their generous support of our programs. We also gratefully acknowledge the Washington University High Resolution NMR facility, partially supported by NIH grants RR02004, RR05018, and RR07155, and the Washington University Mass Spectrometry Resource Center, partially supported by NIHRR00954, for their assistance.",
year = "2003",
month = oct,
day = "20",
doi = "10.1016/j.tet.2003.09.027",
language = "English",
volume = "59",
pages = "8515--8523",
journal = "Tetrahedron",
issn = "0040-4020",
number = "43",
}