Considerations and alternative approaches to antibiotic prophylaxis for prostate biopsy

Eric H. Kim, Gerald L. Andriole

Research output: Contribution to journalArticlepeer-review

Abstract

In this study of culture-specific antibiograms from six hospitals in the Philadelphia region, the authors compare American Urological Association (AUA) recommendations for prostate biopsy prophylaxis against the common urinary pathogens, E. coli, Klebsiella, and Proteus.1 The authors examine the sensitivity of these pathogens to the most commonly utilized antibiotics for biopsy prophylaxis, including fluoroquinolones (FQ), trimethoprim/ sulfamethoxazole (TMP/SMX), gentamicin, and ceftriaxone. The results are alarming, with E. coli resistance to FQ and TMP/SMX ranging from 20% to 32%; Klebsiella resistance to FQ and TMP/SMX ranging from 6% to 22%; Proteus resistance to FQ and TMP/SMX ranging from 10 to 32%.

Original languageEnglish
Pages (from-to)10105
Number of pages1
JournalCanadian Journal of Urology
Volume27
Issue number1
StatePublished - 2020

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