Consecutive Reactions in Triple Analyzer Mass Spectrometry and Applications to Mixture Analysis

David J. Burlnsky; R. Graham Cooks; Edward K. Chess; Michael L. Gross

doi:10.1021/ac00239a034

Consecutive Reactions in Triple Analyzer Mass Spectrometry and Applications to Mixture Analysis

David J. Burlnsky, R. Graham Cooks, Edward K. Chess, Michael L. Gross

Research output: Contribution to journal › Article › peer-review

109 Scopus citations

Abstract

A unique application of triple analyzer mass spectrometers Is based on the capability for observing consecutive collisioninduced reactions In various zones of the Instrument. Ions are activated In the first field free region and a specific decomposition product Is selected by using the first two analyzers-an electrostatic and a magnetic sector. The Ion Is then submitted to collisional activation In the third field free region, and the decomposition products are analyzed by using the third sector, a second electrostatic analyzer. It Is demonstrated that high-quality spectra can be obtained which compare favorably with normal mass spectrometry/mass spectrometry spectra. Two applications shown to be feasible Involve analysis of mixtures of Ions which are Isobarlc and Isomeric, respectively.

Original language	English
Pages (from-to)	295-299
Number of pages	5
Journal	Analytical Chemistry
Volume	54
Issue number	2
DOIs	https://doi.org/10.1021/ac00239a034
State	Published - Feb 1982

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title = "Consecutive Reactions in Triple Analyzer Mass Spectrometry and Applications to Mixture Analysis",

abstract = "A unique application of triple analyzer mass spectrometers Is based on the capability for observing consecutive collisioninduced reactions In various zones of the Instrument. Ions are activated In the first field free region and a specific decomposition product Is selected by using the first two analyzers-an electrostatic and a magnetic sector. The Ion Is then submitted to collisional activation In the third field free region, and the decomposition products are analyzed by using the third sector, a second electrostatic analyzer. It Is demonstrated that high-quality spectra can be obtained which compare favorably with normal mass spectrometry/mass spectrometry spectra. Two applications shown to be feasible Involve analysis of mixtures of Ions which are Isobarlc and Isomeric, respectively.",

author = "Burlnsky, {David J.} and Cooks, {R. Graham} and Chess, {Edward K.} and Gross, {Michael L.}",

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AU - Burlnsky, David J.

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AU - Chess, Edward K.

AU - Gross, Michael L.

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Y1 - 1982/2

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AB - A unique application of triple analyzer mass spectrometers Is based on the capability for observing consecutive collisioninduced reactions In various zones of the Instrument. Ions are activated In the first field free region and a specific decomposition product Is selected by using the first two analyzers-an electrostatic and a magnetic sector. The Ion Is then submitted to collisional activation In the third field free region, and the decomposition products are analyzed by using the third sector, a second electrostatic analyzer. It Is demonstrated that high-quality spectra can be obtained which compare favorably with normal mass spectrometry/mass spectrometry spectra. Two applications shown to be feasible Involve analysis of mixtures of Ions which are Isobarlc and Isomeric, respectively.

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JO - Analytical Chemistry

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Consecutive Reactions in Triple Analyzer Mass Spectrometry and Applications to Mixture Analysis

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