Connectivity optimization and the positioning of cortical areas

Vitaly A. Klyachko, Charles F. Stevens

Research output: Contribution to journalArticlepeer-review

162 Scopus citations


By examining many alternative arrangements of cortical areas, we have found that the arrangement actually present in the brain minimizes the volume of the axons required for interconnecting the areas. Our observations support the notion that the organization of cortical areas has evolved to optimize interareal connections.

Original languageEnglish
Pages (from-to)7937-7941
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Issue number13
StatePublished - Jun 24 2003


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