Conjunctival condylomata acuminata

PURPOSE: To report a case of sexually transmitted conjunctival squamous papilomas and to propose a new term for this condition. METHODS: We report a case of a 31-year-old white woman who presented with bilateral exuberant conjunctival papillomas. Her medical history included biopsy-proven human papillomavirus-induced genital warts, of which she was currently having a recurrence. We treated her eyes with topical a-interferon 2b. RESULTS: After treatment, there was significant reduction of the conjunctival lesions. Tissue from a conjunctival lesion of her left eye showed a papillary squamous proliferation with delicated fibrovascular cores and acanthotic epithelium containing binucleate cells and koilocytes. Molecular testing confirmed the lesion to harbor human papillomavirus type 11. CONCLUSIONS: The term "condylomata acuminata" typically refers to anogenital warts. From the similarities between the conjunctival lesions described in this patient and typical genital warts, it is our recommendation to refer to these lesions as conjunctival condylomata acuminata. This diagnostic term connotes a sexually transmitted etiology and should alert the health care provider to look for possible asymptomatic genital warts on the patient or the patient's sexual partner.