Congenital neuroblastoma

Elena Minakova, Jordan Lang

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Neuroblastoma is the most common extracranial solid tumor diagnosed during childhood and gives rise to various heterogeneous tumors along the sympathoadrenal axis. Congenital neuroblastoma accounts for 5% of total neuroblastoma cases diagnosed annually, with the majority of cases diagnosed in the first month after birth. Interestingly, neonates demonstrate a unique disease trajectory compared with children older than 1 year of age. This article will provide information on the pathogenesis and variable clinical presentation of congenital neuroblastoma, along with the biological prognostic factors that predict long-term outcomes in affected neonates.

Original languageEnglish
Pages (from-to)e716-e727
JournalNeoReviews
Volume21
Issue number11
DOIs
StatePublished - Nov 1 2020

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