Congenital insensitivity to pain: Fracturing without apparent skeletal pathobiology caused by an autosomal dominant, second mutation in SCN11A encoding voltage-gated sodium channel 1.9

Medicine & Life Sciences

• Congenital Pain Insensitivity 100%
• Voltage-Gated Sodium Channels 78%
• Joint Instability 56%
• Gain of Function Mutation 37%
• Histology 34%
• Ilium 33%
• Mutation 32%
• NAV1.9 Voltage-Gated Sodium Channel 29%
• Minerals 27%
• Child 24%
• Diarrhea 23%
• Homeostasis 21%
• Hyperhidrosis 19%
• Multiple Fractures 19%
• Hypertrophic Cicatrix 19%
• Mothers 18%
• Bone and Bones 17%
• Ankle Joint 16%
• Neural Conduction 16%
• Tetracycline 15%
• Peripheral Nervous System Diseases 15%
• Missense Mutation 14%
• Electromyography 14%
• Wounds and Injuries 13%
• Physical Examination 12%
• Single Nucleotide Polymorphism 12%
• Exons 11%
• Hip 11%
• Lower Extremity 11%
• Spine 11%
• Collagen 10%
• Joints 10%
• Amino Acids 10%
• Databases 8%
• Pain 8%
• DNA 8%
• Skin 7%