Congenital Hyperinsulinism

Augusto Zani; Agostino Pierro

doi:10.1007/978-3-662-43588-5_65

Congenital Hyperinsulinism

Augusto Zani
, Agostino Pierro

Division of Pediatric Surgery

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Congenital hyperinsulinism (CHI) comprises a group of disorders characterized by excessive insulin secretion from pancreatic β-cells, resulting in severe hypoglycemia. In neonates and infants, CHI is considered the most frequent cause of persistent hypoglycemia. Prompt diagnosis and treatment are crucial as a delay may cause severe brain damage and long-term neurodevelopmental disability. Therapeutic strategies for CHI can be medical, surgical, or combined.

Original language	English
Title of host publication	Pediatric Surgery
Subtitle of host publication	General Principles and Newborn Surgery: Volume 1
Publisher	Springer Berlin Heidelberg
Pages	905-911
Number of pages	7
Volume	1
ISBN (Electronic)	9783662435885
ISBN (Print)	9783662435878
DOIs	https://doi.org/10.1007/978-3-662-43588-5_65
State	Published - Jan 1 2020

Keywords

Congenital hyperinsulinism
Hypoglycemia
Pancreatectomy
Persistent hyperinsulinism
Transient hyperinsulinism

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10.1007/978-3-662-43588-5_65

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abstract = "Congenital hyperinsulinism (CHI) comprises a group of disorders characterized by excessive insulin secretion from pancreatic β-cells, resulting in severe hypoglycemia. In neonates and infants, CHI is considered the most frequent cause of persistent hypoglycemia. Prompt diagnosis and treatment are crucial as a delay may cause severe brain damage and long-term neurodevelopmental disability. Therapeutic strategies for CHI can be medical, surgical, or combined.",

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KW - Hypoglycemia

KW - Pancreatectomy

KW - Persistent hyperinsulinism

KW - Transient hyperinsulinism

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ER -

Congenital Hyperinsulinism

Abstract

Keywords

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