Congenital herpes simplex retinitis

James D. Reynolds, May Griebel, Susan Mallory, Russell Steele

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


An 1,810-g girl born at 37 weeks of gestation had true congenital herpes simplex virus type 2 infection. The neonate was born with hypo-pigmented skin lesions, brain lesions, and old heavily pigmented retinal scars in the posterior pole. There was no active ocular disease. Viral cultures, immunoperoxidase stains, and antibody determination by enzyme-linked immunosorbent assay were all positive for herpes simplex virus. Treatment with acyclovir healed the lesions within ten days. The clinical and laboratory findings indicated that the herpetic infection probably occurred in the second trimester.

Original languageEnglish
Pages (from-to)33-36
Number of pages4
JournalAmerican journal of ophthalmology
Issue number1
StatePublished - Jul 15 1986


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