@article{55f24f045a5344dabcd691bcbc85e739,
title = "Conformational probes for elucidating the nature of substance P binding to the NK1 receptor: Initial efforts to map the Phe7-Phe8 region",
abstract = "Three substance P analogs with conformation constraints in the Phe7- Phe8 region have been prepared in connection with an effort to differentiate two families of potential conformations for the binding of substance P to its NK1 receptor. While the analogs did not bind the NK1 receptor with high affinity, the synthesis of the analogs demonstrated the utility of a general method for constructing piperazinone based peptidomimetics.",
author = "Yunsong Tong and Fobian, {Yvette M.} and Meiye Wu and Boyd, {Norman D.} and Moeller, {Kevin D.}",
note = "Funding Information: Acknowledgements: We thank the National Institutes of Health (ROl GM5324001Al) for their generous financial support. In addition, we thank the Washington University High Resolution NMR Facility, partially supported by NIH grants RRO2004, RR050 18, and RR07 155, and the Washington University Mass Spectrometry Resource Center, partially supported by NIH RR00954, for their assistance.",
year = "1998",
month = jul,
day = "7",
doi = "10.1016/S0960-894X(98)00289-3",
language = "English",
volume = "8",
pages = "1679--1682",
journal = "Bioorganic and Medicinal Chemistry Letters",
issn = "0960-894X",
number = "13",
}