Abstract
This chapter describes design and implementation considerations for clinical trials that evaluate behavioral interventions in hospice and palliative care. We discuss traditional and emerging approaches to randomization and data analysis, considering the unique challenges of the setting including the unpredictable and often stressful conditions that participants find themselves in when dealing with advanced illness and how these affect their ability to participate in prescribed and standardized study procedures. In addition, we discuss considerations for recruitment and retention of participants and methodological approaches such as intention to treat. We also explore options for economic considerations when evaluating an intervention.
Original language | English |
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Title of host publication | Behavioral Intervention Research in Hospice and Palliative Care |
Subtitle of host publication | Building an Evidence Base |
Publisher | Elsevier |
Pages | 75-94 |
Number of pages | 20 |
ISBN (Electronic) | 9780128144497 |
ISBN (Print) | 9780128144503 |
DOIs | |
State | Published - Jan 1 2019 |
Keywords
- Clinical trial
- cost analysis
- intention to treat
- participant recruitment and retention
- pragmatic trial
- randomization