Conditional HIF-1 induction produces multistage neovascularization with stage-specific sensitivity to VEGFR inhibitors and myeloid cell independence

Keyphrases

• 3-stage 16%
• Adult Mice 16%
• Angiogenesis Inhibitors 16%
• Arteriovenous 16%
• Conditional Model 16%
• Crucial Component 16%
• DC101 16%
• Developmental Stages 33%
• Disease Model 16%
• DNA Damage Checkpoint 16%
• Endothelial Proliferation 16%
• H2AX 16%
• Hypoxia-inducible factor-1α (HIF-1α) 100%
• Illness 16%
• Immuno 33%
• Inhibitor Resistance 16%
• Intrinsic Mechanism 16%
• Label-free 16%
• Maintenance Stage 16%
• Microscopic Analysis 16%
• Microvascular Architecture 16%
• Microvessels 50%
• Morphogenesis 16%
• Myeloid Cells 100%
• Neovascularization 100%
• Neovasculature 16%
• Non-cell Autonomous 16%
• P-53 16%
• Pericyte Coverage 16%
• Photoacoustic Microscopy 50%
• Red Blood 16%
• Serial Imaging 16%
• Specific Susceptibility 100%
• Tight 16%
• Tumor Growth 16%
• Tumor Ischemia 16%
• Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) 33%
• Vasculature 16%
• VEGF Inhibitors 100%
• VEGFR-2 Inhibitors 16%
• Volumetric Change 16%

Medicine and Dentistry

• Angiogenesis Inhibitor 33%
• Developmental Stage 66%
• Disease Model 33%
• Diseases 100%
• DNA Damage Checkpoint 33%
• Downregulation 33%
• Immunoglobulin 66%
• Ischemia 33%
• Microvessel 100%
• Monoclonal Antibody DC101 33%
• Morphogenesis 33%
• Myeloid Cell 100%
• P21 33%
• Pericyte 33%
• Photoacoustic Microscopy 100%
• Protein P53 33%
• Transgene 33%
• Tumor Progression 33%
• Vascularity 33%