TY - JOUR
T1 - Computed Tomography in Chronic Seizure Disorder Caused by Glioma
AU - Rich, Keith M.
AU - Goldring, Sidney
AU - Gado, Mokhtar
PY - 1985/1
Y1 - 1985/1
N2 - Since the introduction of computed tomography (CT) in 1974, 137 patients underwent cortical resection for intractable epilepsy. The CT scans of 32 of these patients demonstrated an isolated calcified or hypodense lesion of unknown origin. The mean interval from onset of the seizure disorder to surgery was 11 years. The referring physicians frequently considered these lesions to be of nonneoplastic origin, which usually delayed surgical management. Twenty-six of the 32 patients, however, proved to have a cerebral glioma, seven showing anaplastic changes. Because the majority of these patients were found to have a neoplasm and especially because the CT scan could not distinguish between a well-differentiated glioma and those with anaplastic changes, we recommend early surgical treatment in patients with chronic seizure disorders who are found to have an isolated lesion of unknown origin on CT scan.
AB - Since the introduction of computed tomography (CT) in 1974, 137 patients underwent cortical resection for intractable epilepsy. The CT scans of 32 of these patients demonstrated an isolated calcified or hypodense lesion of unknown origin. The mean interval from onset of the seizure disorder to surgery was 11 years. The referring physicians frequently considered these lesions to be of nonneoplastic origin, which usually delayed surgical management. Twenty-six of the 32 patients, however, proved to have a cerebral glioma, seven showing anaplastic changes. Because the majority of these patients were found to have a neoplasm and especially because the CT scan could not distinguish between a well-differentiated glioma and those with anaplastic changes, we recommend early surgical treatment in patients with chronic seizure disorders who are found to have an isolated lesion of unknown origin on CT scan.
UR - http://www.scopus.com/inward/record.url?scp=0021914238&partnerID=8YFLogxK
U2 - 10.1001/archneur.1985.04060010032011
DO - 10.1001/archneur.1985.04060010032011
M3 - Article
C2 - 3966881
AN - SCOPUS:0021914238
SN - 0003-9942
VL - 42
SP - 26
EP - 27
JO - Archives of neurology
JF - Archives of neurology
IS - 1
ER -