TY - JOUR
T1 - Computed radiography versus screen-film radiography
T2 - Detection of pulmonary edema in a rabbit model that simulates neonatal pulmonary infiltrates
AU - Don, Steven
AU - Hildebolt, Charles F.
AU - Sharp, Terry L.
AU - Shackelford, Gary D.
AU - Lau, Debra M.
AU - Herman, Thomas E.
AU - McAlister, William H.
N1 - Funding Information:
A.L. and M.S. were supported by a DOC fellowship of the Austrian Academy of Sciences. Z.K. was supported by a fellowship of the Marie Sk?odowska-Curie Actions (MSCA) Innovative Training Network H2020-MSCAITN-2019 (grant agreement no. 813343). B.A. was supported by the Austrian Science Fund (FWF) PhD program in Inflammation and Immunity (FWF1212). C.B. and A.B. were supported by ERC Starting Grants (European Union's Horizon 2020 research and innovation programme, grant agreement numbers 679146 and 677006, respectively). This project was funded, in part, by the Vienna Science and Technology Fund (WWTF) as part of the WWTF COVID-19 Rapid Response Funding 2020 (to A.B.).
PY - 1999/11
Y1 - 1999/11
N2 - PURPOSE: To determine if computed radiography is equivalent to screen- film radiography in depicting pulmonary edema and to determine if radiation exposure can be reduced with computed radiography while maintaining equivalent diagnostic accuracy for pulmonary edema. MATERIALS AND METHODS: Oleic acid was intravenously injected into three rabbits at each of four doses: 0, 0.02, 0.04, and 0.06 mL/kg. Two hours later, chest computed radiographs and screen-film radiographs were obtained at 60 kVp and 1.1 mAs. Additional computed radiographs were obtained after reducing milliampere seconds or by reducing milliampere seconds and increasing the kilovolt peak, which reduced bone marrow exposure by up to 20%. The presence of pulmonary opacities, 'truth,' was established by the wet-dry weight ratio and by chest computed tomography (CT). The radiographs were masked and randomized. Four observers rated the images for the presence of parenchymal opacities with a dichotomous score and judged the quality of the radiographs on a scale from 1 (worst) to 6 (best). Cochran Q tests and McNemar tests were used to analyze the differences in paired comparisons. Image quality was evaluated with logistic regression analysis. RESULTS: There was no significant difference between truth and observer ability to detect opacity for either modality or for any exposure (P > .05). There was no significant difference between computed radiography and screen-film radiography for image quality (P > .05). CONCLUSION: Computed radiography is equivalent to screen-film radiography in the detection of pulmonary edema. Radiation exposure reduction of 20% can be achieved without affecting pulmonary edema detection or image quality.
AB - PURPOSE: To determine if computed radiography is equivalent to screen- film radiography in depicting pulmonary edema and to determine if radiation exposure can be reduced with computed radiography while maintaining equivalent diagnostic accuracy for pulmonary edema. MATERIALS AND METHODS: Oleic acid was intravenously injected into three rabbits at each of four doses: 0, 0.02, 0.04, and 0.06 mL/kg. Two hours later, chest computed radiographs and screen-film radiographs were obtained at 60 kVp and 1.1 mAs. Additional computed radiographs were obtained after reducing milliampere seconds or by reducing milliampere seconds and increasing the kilovolt peak, which reduced bone marrow exposure by up to 20%. The presence of pulmonary opacities, 'truth,' was established by the wet-dry weight ratio and by chest computed tomography (CT). The radiographs were masked and randomized. Four observers rated the images for the presence of parenchymal opacities with a dichotomous score and judged the quality of the radiographs on a scale from 1 (worst) to 6 (best). Cochran Q tests and McNemar tests were used to analyze the differences in paired comparisons. Image quality was evaluated with logistic regression analysis. RESULTS: There was no significant difference between truth and observer ability to detect opacity for either modality or for any exposure (P > .05). There was no significant difference between computed radiography and screen-film radiography for image quality (P > .05). CONCLUSION: Computed radiography is equivalent to screen-film radiography in the detection of pulmonary edema. Radiation exposure reduction of 20% can be achieved without affecting pulmonary edema detection or image quality.
KW - Computed tomography (CT), comparative studies
KW - Lung, fluid
KW - Radiography, comparative studies
KW - Radiography, in infants and children
KW - Radiography, storage phosphor
UR - http://www.scopus.com/inward/record.url?scp=0032738191&partnerID=8YFLogxK
U2 - 10.1148/radiology.213.2.r99nv15455
DO - 10.1148/radiology.213.2.r99nv15455
M3 - Article
C2 - 10551226
AN - SCOPUS:0032738191
SN - 0033-8419
VL - 213
SP - 455
EP - 460
JO - Radiology
JF - Radiology
IS - 2
ER -