Computational Stem Cell Biology: Open Questions and Guiding Principles

Patrick Cahan, Davide Cacchiarelli, Sara Jane Dunn, Martin Hemberg, Susana M.Chuva de Sousa Lopes, Samantha A. Morris, Owen J.L. Rackham, Antonio del Sol, Christine A. Wells

Research output: Contribution to journalReview articlepeer-review

22 Scopus citations

Abstract

Cahan and colleagues analyze how computational principles are best applied to stem cell biology. They focus on cell typing, lineage tracing, trajectory inference, and regulatory networks as examples articulating principles that have guided computational biology broadly and call for renewed attention to these principles as applied in stem cell research.

Original languageEnglish
Pages (from-to)20-32
Number of pages13
JournalCell Stem Cell
Volume28
Issue number1
DOIs
StatePublished - Jan 7 2021

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