Computational fluid dynamic analysis of a blood pump: An FDA critical path initiative

Christopher J. Nassau, Timothy J. Wray, Ramesh K. Agarwal

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Scopus citations


Computational Fluid Dynamics (CFD) has become a routine tool in recent times for use in blood-contacting medical device design and analysis, such as prosthetic heart valves and ventricular assist devices (VADs). While CFD can aid in design by decreasing the need for expensive prototyping and iterative laboratory testing, standardizations are not currently available for CFD to be used for medical device safety analysis at the preclinical stage. To address this, the U.S. Food and Drug Administration (FDA)'s Center of Devices and Radiological Health (CDRH) has sponsored CFD "round-robins." This paper focuses on Computational Round Robin #2 - Model Blood Pump. The exact geometries, flow conditions and fluid characteristics for the CFD analysis have been supplied to the participants. In the CFD analysis presented in this paper, a rotating fluid zone around the pump impeller was used to avoid the complexities of a dynamic mesh. The rotating fluid zone was modeled by including the centrifugal and Coriolis forces in the Navier-Stokes equations. The Shear Stress Transport (SST) k-ω turbulence model was used and the steady-state solutions for the desired flow conditions were calculated. Current experimental data is still being collected by FDA for the flow conditions given in the study. However, some of the pump operating characteristics are available from work of other investigators and are used to validate the CFD results.

Original languageEnglish
Title of host publicationFora
PublisherAmerican Society of Mechanical Engineers
ISBN (Electronic)9780791857229
StatePublished - 2015
EventASME/JSME/KSME 2015 Joint Fluids Engineering Conference, AJKFluids 2015 - Seoul, Korea, Republic of
Duration: Jul 26 2015Jul 31 2015

Publication series

NameASME/JSME/KSME 2015 Joint Fluids Engineering Conference, AJKFluids 2015


ConferenceASME/JSME/KSME 2015 Joint Fluids Engineering Conference, AJKFluids 2015
Country/TerritoryKorea, Republic of


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