TY - JOUR
T1 - Compton scattering in clinical PET/CT with high resolution half ring PET insert device
AU - Komarov, Sergey A.
AU - Wu, Heyu
AU - Keesing, Daniel B.
AU - O'Sullivan, Joseph A.
AU - Tai, Yuan Chuan
N1 - Funding Information:
Manuscript received December 15, 2009; revised March 16, 2010; accepted March 19, 2010. Date of current version June 16, 2010. This work was supported in part under Grants by the National Cancer Institute of the National Institutes of Health (R33-CA110011, R24-CA83060, and P30-CA91842) and by Susan G. Komen for the Cure (BCTR0601279).
PY - 2010/6
Y1 - 2010/6
N2 - The integration of a high resolution PET insert into a conventional PET system can significantly improve the resolution and the contrast of its images within a reduced imaging field of view. For the rest of the scanner imaging field of view, the insert is a highly attenuating and scattering media. In order to use all available coincidence events (including coincidences between 2 detectors in the original scanner, namely the scanner-scanner coincidences), appropriate scatter and attenuation corrections have to be implemented. In this work, we conducted a series of Monte Carlo simulations to estimate the composition of the scattering background and the importance of the scatter correction. We implemented and tested the Single Scatter Simulation (SSS) algorithm for a hypothetical system and show good agreement between the estimated scatter using SSS and Monte Carlo simulated scatter contribution. We further applied the SSS to estimate scatter contribution from an existing prototype PET insert for a clinical PET/CT scanner. The results demonstrated the applicability of SSS to estimate the scatter contribution within a clinical PET/CT system even when there is a high resolution half ring PET insert device in its imaging field of view.
AB - The integration of a high resolution PET insert into a conventional PET system can significantly improve the resolution and the contrast of its images within a reduced imaging field of view. For the rest of the scanner imaging field of view, the insert is a highly attenuating and scattering media. In order to use all available coincidence events (including coincidences between 2 detectors in the original scanner, namely the scanner-scanner coincidences), appropriate scatter and attenuation corrections have to be implemented. In this work, we conducted a series of Monte Carlo simulations to estimate the composition of the scattering background and the importance of the scatter correction. We implemented and tested the Single Scatter Simulation (SSS) algorithm for a hypothetical system and show good agreement between the estimated scatter using SSS and Monte Carlo simulated scatter contribution. We further applied the SSS to estimate scatter contribution from an existing prototype PET insert for a clinical PET/CT scanner. The results demonstrated the applicability of SSS to estimate the scatter contribution within a clinical PET/CT system even when there is a high resolution half ring PET insert device in its imaging field of view.
KW - Compton scattering
KW - Image resolution
KW - Positron emission tomography
KW - Single scatter simulation
UR - http://www.scopus.com/inward/record.url?scp=77953726897&partnerID=8YFLogxK
U2 - 10.1109/TNS.2010.2046754
DO - 10.1109/TNS.2010.2046754
M3 - Article
C2 - 21552470
AN - SCOPUS:77953726897
SN - 0018-9499
VL - 57
SP - 1045
EP - 1051
JO - IEEE Transactions on Nuclear Science
JF - IEEE Transactions on Nuclear Science
IS - 3 PART 1
M1 - 5485098
ER -