Comprehensive single-cell transcriptional profiling defines shared and unique epithelial injury responses during kidney fibrosis

Keyphrases

• Fibrogenesis 100%
• Injury Response 100%
• Kidney Fibrosis 100%
• Epithelial Injury 100%
• Single-cell Transcriptional Profiling 100%
• Lipid Metabolism 50%
• Dysregulated 50%
• RNA Sequencing (RNA-seq) 50%
• Knockdown 50%
• Kidney 50%
• Epithelial Cells 50%
• Ischemia 50%
• Proximal Tubule 50%
• Cellular Events 50%
• Stromal Cells 50%
• Mouse Kidney 50%
• Perilipin 2 50%
• Fatty Acid Oxidation 50%
• Chronic Phase 50%
• Amino Acid Metabolism 50%
• Epithelial-mesenchymal Interaction 50%
• Surface Markers 50%
• Lipid Droplets 50%
• Fibrosis Models 50%
• Lipid Accumulation 50%
• Intracellular Lipids 50%
• Single-cell Analysis 50%
• Metabolic Dysfunction 50%
• Lipid Deposition 50%
• Nephron Segments 50%
• High Heterogeneity 50%
• Energy State 50%
• Lipid Acids 50%
• Cell Energy 50%
• Single-cell Combinatorial Indexing 50%
• State Maintenance 50%

Biochemistry, Genetics and Molecular Biology

• Gene Expression Profiling 100%
• Lipid Storage 100%
• Fibrogenesis 100%
• Lipid Metabolism 50%
• RNA Sequence 50%
• Lipid 50%
• Stromal Cell 50%
• Beta Oxidation 50%
• Lipid Droplet 50%
• Perilipin 50%
• Cell Energy 50%
• Amino Acid Metabolism 50%
• Immunity 50%
• Single-Cell Analysis 50%

Immunology and Microbiology

• Fibrogenesis 100%
• Lipid Storage 100%
• Gene Expression Assay 100%
• Lipid Metabolism 50%
• Nephron 50%
• RNA Sequence 50%
• Immunity 50%
• Amino Acid Metabolism 50%
• Fatty Acid Oxidation 50%
• Single Cell Analysis 50%
• Cell Energy 50%