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Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment
The NCI PDXNet Consortium
Section of Medical Oncology
Section of Molecular Oncology & Developmental Therapeutics
Bursky Center for Human Immunology & Immunotherapy Programs (CHiiPs)
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
Institute of Clinical and Translational Sciences (ICTS)
Siteman Cancer Center
Section of Surgical Oncology
Department of Otolaryngology
Division of Oncology
Division of Public Health Sciences
Institute for Public Health
Division of General Surgery
Section of Computational Biology
Center of Regenerative Medicine
Rheumatic Diseases Research Resource-Based Center
DBBS - Molecular Cell Biology
DBBS - Immunology
DBBS - Cancer Biology
DBBS - Molecular Genetics and Genomics
DBBS - Computational and Systems Biology
DBBS - Developmental, Regenerative and Stem Cell Biology
DBBS - Biomedical Informatics and Data Science
DBBS - Biochemistry, Biophysics, and Structural Biology
Brain Tumor Center
Department of Mechanical Engineering & Materials Science
Mentorship to Enhance Diversity in Academia (MEDA)
Section of Bone Marrow Transplant & Leukemia
Research output
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Contribution to journal
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Article
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peer-review
72
Scopus citations
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Keyphrases
Patient-derived Xenograft
100%
Targeted Treatment
100%
Comprehensive Characterization
100%
Human Tumors
50%
Genomic Landscape
50%
NCI-MATCH
50%
Cancer Types
25%
Subclone
25%
Cancer Patients
25%
Cancer Treatment
25%
Copy number
25%
Genetic Profile
25%
Pharmacogenomics
25%
Druggability
25%
Molecular Properties
25%
Genomic Characterization
25%
Transcriptome Profile
25%
Recapitulation
25%
Whole Genome Duplication
25%
Pan-cancer
25%
Driver Events
25%
Source Code
25%
High Purity
25%
Multiple Time Points
25%
Web Portal
25%
Event Properties
25%
Dynamic Driver
25%
Biochemistry, Genetics and Molecular Biology
Genomics
100%
Transcriptomics
25%
Pharmacogenomics
25%
Pan-cancer
25%