TY - JOUR
T1 - Complication Rates and Maintenance of Correction after 3-Column Osteotomy in the Elderly
T2 - Report of 55 Patients with 2-Year Follow-up
AU - Challier, Vincent
AU - Henry, Jensen K.
AU - Liu, Shian
AU - Ames, Christopher
AU - Kebaish, Khaled
AU - Obeid, Ibrahim
AU - Hostin, Richard
AU - Gupta, Munish
AU - Boachie-Adjei, Oheneba
AU - Smith, Justin S.
AU - Mundis, Gregory
AU - Bess, Shay
AU - Schwab, Frank
AU - Lafage, Virginie
N1 - Funding Information:
Data collection for the database used in this study was supported by a grant from Depuy to the International Spine Study Group Foundation. No specific sources of funding were provided for this study in particular. Dr Ames is a consultant for DePuy, Medtronic, and Stryker; holds patents with Fisch & Richardson P C; receives royalties from Stryker and Biomet Spine; and has Stock/stock options with Doctor’s Research Group and Visulase. Dr Kebaish receives support from Depuy Synthes, K2M, and Orthofix. Dr Obeid receives support from DePuy Synthes and Medtronic. Dr Hostin is a consultant for Depuy Synthes Spine and receives grants from Depuy Syntheis Spine, Nuvasive, Seeger, DJO, and K2M. Dr Gupta receives royalties from Depuy Synthes, is a consultant for Medtronic, Orthofix, Depuy, and Medicrea, and holds stock with Johnson & Johnson, Proctor and Gamble, Pfizer, and Pioneer. Dr Boachie-Adjei discloses relationships with K2M and Weigao. Dr Smith is a consultant for Biomet, Nuvasive, Cerapedics, Depuy, and Globus, has give expert testimony for multiple legal firms, and receives royalties from Biomet. Dr Mundis receives royalties from Nuvasive and K2M, is a consultant for Nuvasive, K2M, Misonix, and Medicrea. Dr Bess receives support from Depuy, Allosource, and Pioneer Spine. Dr Schwab discloses board membership with Nemaris Inc, is a consultant for MSD, Medicrea, and K2M, has received grants from Depuy, MSD, and AO, has received payment for manuscript preparation from MSD, Nuvasive, Biomet, K2M, and Nemaris Inc, has patents with MSD, K2M, and Nemaris Inc, and receives royalties from MSD and K2M. Dr Lafage discloses board membership with Nemaris Inc, grants from SRS, NIH, and Depuy, payment for lectures from Medicrea, Nemaris Inc, MSD, and Depuy, and Stock/stock options with Nemaris Inc. The authors have no personal, financial, or institutional interest in any of the drugs, materials, or devices described in this article.
Publisher Copyright:
© 2017 by the Congress of Neurological Surgeons.
PY - 2018/11/1
Y1 - 2018/11/1
N2 - BACKGROUND: Three-column osteotomies (3CO) provide substantial correction for adult spinal deformity (ASD), but carry risks of complications and revisions. The risk-benefit balance of 3CO in the elderly remains unclear. OBJECTIVE: To evaluate sagittal alignment and complications after 3CO in a population over 70-yr old. METHODS:Radiographic retrospective review of consecutive patients over 70 yr (Elderly) undergoing 3CO for ASD. Demographic, operative, and outcomes data were collected. Full-spine radiographs were analyzed at baseline and 2-yr postoperatively. Results were compared to a group of young controls (Young) matched by global sagittal alignment. RESULTS: Elderly (n = 55) and Young (n = 52) were similar in operating room time, blood loss, levels fused, and revision surgeries. Elderly and Young groups had similar baseline radiographic malalignment for pelvic tilt, pelvic incidence-lumbar lordosis (PI-LL), and sagittal vertical axis (P > .5 for all). At 2-yr postoperatively, both groups underwent significant improvement in the setting of sagittal alignment parameters (Elderly: sagittal vertical axis 150mmto 59 mm, P<.001; pelvic tilt 33? to 25?, P<.001; PI-LL 35? to PI-LL 6?, P<.001). However, the Elderly group underwent significantly greater correction in PI-LL than the Young group (-29? vs -20?, P = .024). There were no differences in total, intraoperative or postoperative complications or revisions between groups, though the Elderly group had more intraoperative complicationswhenmajor blood loss was included. The Elderly group had more severe proximal junctional kyphosis (22.1? vs 9.6? in Young; P < .001). CONCLUSION: Compared to young patients, elderly patients may achieve the same, or even better, correction in radiographic spinopelvic parameters. In addition, not only the total intraoperative and postoperative complication rates but also revision rates were comparable between both groups.
AB - BACKGROUND: Three-column osteotomies (3CO) provide substantial correction for adult spinal deformity (ASD), but carry risks of complications and revisions. The risk-benefit balance of 3CO in the elderly remains unclear. OBJECTIVE: To evaluate sagittal alignment and complications after 3CO in a population over 70-yr old. METHODS:Radiographic retrospective review of consecutive patients over 70 yr (Elderly) undergoing 3CO for ASD. Demographic, operative, and outcomes data were collected. Full-spine radiographs were analyzed at baseline and 2-yr postoperatively. Results were compared to a group of young controls (Young) matched by global sagittal alignment. RESULTS: Elderly (n = 55) and Young (n = 52) were similar in operating room time, blood loss, levels fused, and revision surgeries. Elderly and Young groups had similar baseline radiographic malalignment for pelvic tilt, pelvic incidence-lumbar lordosis (PI-LL), and sagittal vertical axis (P > .5 for all). At 2-yr postoperatively, both groups underwent significant improvement in the setting of sagittal alignment parameters (Elderly: sagittal vertical axis 150mmto 59 mm, P<.001; pelvic tilt 33? to 25?, P<.001; PI-LL 35? to PI-LL 6?, P<.001). However, the Elderly group underwent significantly greater correction in PI-LL than the Young group (-29? vs -20?, P = .024). There were no differences in total, intraoperative or postoperative complications or revisions between groups, though the Elderly group had more intraoperative complicationswhenmajor blood loss was included. The Elderly group had more severe proximal junctional kyphosis (22.1? vs 9.6? in Young; P < .001). CONCLUSION: Compared to young patients, elderly patients may achieve the same, or even better, correction in radiographic spinopelvic parameters. In addition, not only the total intraoperative and postoperative complication rates but also revision rates were comparable between both groups.
KW - 3-column osteotomy
KW - Complications
KW - Elderly
KW - Pedicle subtraction osteotomy
KW - Sagittal alignment
KW - Spinal deformity
KW - Spine
UR - http://www.scopus.com/inward/record.url?scp=85052807996&partnerID=8YFLogxK
U2 - 10.1093/neuros/nyx580
DO - 10.1093/neuros/nyx580
M3 - Article
C2 - 29281113
AN - SCOPUS:85052807996
SN - 0069-4827
VL - 83
SP - 973
EP - 980
JO - Clinical Neurosurgery
JF - Clinical Neurosurgery
IS - 5
ER -