TY - JOUR
T1 - Compliance with topical timolol treatment
AU - Kass, M. A.
AU - Gordon, M.
AU - Morley, R. E.
AU - Meltzer, D. W.
AU - Goldberg, J. J.
N1 - Funding Information:
From the Department of Ophthalmology (Drs. Kass, Gordon, and Meltzer), the Division of Biostatistics (Dr. Gordon), the Department of Psychiatry (Mr. Goldberg), and the Department of Electrical Engineering (Dr. Morley), Washington University, St. Louis, Missouri. This study was supported in part by Research Grant EY 03579 and Core Grant EY 02687 from the National Eye Institute, Bethesda, Maryland. The authors have no financial interest in the device described.
PY - 1987
Y1 - 1987
N2 - To determine if compliance with timolol treatment was better than compliance with pilocarpine treatment (as reported previously), we measured compliance with timolol treatment in a sample of 110 patients using an unobtrusive eyedrop medication monitor, which recorded electronically the date and time of each drug administration over a four- to six-week period. The patients administered a mean ± S.D. of 82.7% ± 19.0% of the prescribed timolol doses (range, 20% to 100%). Forty-five patients were treated concurrently with timolol and pilocarpine. These patients administered a mean ± S.D. of 84.3% ± 14.0% of the prescribed pilocarpine doses (P=.012, and van der Waerden test). Our results suggest that while compliance is influenced by the drug regimen, defaulting is not eliminated by prescribing a more convenient medication with fewer side effects.
AB - To determine if compliance with timolol treatment was better than compliance with pilocarpine treatment (as reported previously), we measured compliance with timolol treatment in a sample of 110 patients using an unobtrusive eyedrop medication monitor, which recorded electronically the date and time of each drug administration over a four- to six-week period. The patients administered a mean ± S.D. of 82.7% ± 19.0% of the prescribed timolol doses (range, 20% to 100%). Forty-five patients were treated concurrently with timolol and pilocarpine. These patients administered a mean ± S.D. of 84.3% ± 14.0% of the prescribed pilocarpine doses (P=.012, and van der Waerden test). Our results suggest that while compliance is influenced by the drug regimen, defaulting is not eliminated by prescribing a more convenient medication with fewer side effects.
UR - http://www.scopus.com/inward/record.url?scp=0023146484&partnerID=8YFLogxK
U2 - 10.1016/S0002-9394(14)74225-4
DO - 10.1016/S0002-9394(14)74225-4
M3 - Article
C2 - 3812621
AN - SCOPUS:0023146484
SN - 0002-9394
VL - 103
SP - 188
EP - 193
JO - American journal of ophthalmology
JF - American journal of ophthalmology
IS - 2
ER -