Compliance with topical timolol treatment

M. A. Kass, M. Gordon, R. E. Morley, D. W. Meltzer, J. J. Goldberg

Research output: Contribution to journalArticle

167 Scopus citations

Abstract

To determine if compliance with timolol treatment was better than compliance with pilocarpine treatment (as reported previously), we measured compliance with timolol treatment in a sample of 110 patients using an unobtrusive eyedrop medication monitor, which recorded electronically the date and time of each drug administration over a four- to six-week period. The patients administered a mean ± S.D. of 82.7% ± 19.0% of the prescribed timolol doses (range, 20% to 100%). Forty-five patients were treated concurrently with timolol and pilocarpine. These patients administered a mean ± S.D. of 84.3% ± 14.0% of the prescribed pilocarpine doses (P=.012, and van der Waerden test). Our results suggest that while compliance is influenced by the drug regimen, defaulting is not eliminated by prescribing a more convenient medication with fewer side effects.

Original languageEnglish
Pages (from-to)188-193
Number of pages6
JournalAmerican journal of ophthalmology
Volume103
Issue number2
DOIs
StatePublished - Jan 1 1987

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