Complex and rapid-cycling in bipolar children and adolescents: a preliminary study

Barbara Geller; Kai Sun; Betsy Zimerman; Joan Luby; Jeanne Frazier; Marlene Williams

doi:10.1016/0165-0327(95)00023-G

Complex and rapid-cycling in bipolar children and adolescents: a preliminary study

Barbara Geller, Kai Sun, Betsy Zimerman, Joan Luby, Jeanne Frazier, Marlene Williams

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260 Scopus citations

Abstract

26 subjects aged 7-18 years were studied. Diagnoses of bipolar disorders were established using the Kiddie-Schedule for Affective Disorders and Schizophrenia-Present Episode Version-1986 modified for DSM-III-R criteria and for rating the number and duration of manic and hypomanic episodes. Complex cycling patterns were observed. These included numerous brief episodes suggesting continuous rapid-cycling in 80.8% of cases. Mean age of onset was early (8.5 ± 4.4 years). Psychotic phenomena, suicidality, hyperactivity and 'mixed mania' were highly prevalent. Data in this report provide support for complex and rapid-cycling patterns in childhood onset bipolar disorder.

Original language	English
Pages (from-to)	259-268
Number of pages	10
Journal	Journal of affective disorders
Volume	34
Issue number	4
DOIs	https://doi.org/10.1016/0165-0327(95)00023-G
State	Published - Aug 18 1995

Keywords

Adolescent
Bipolar affective disorder
Child
Hyperactivity
Mixed mania
Rapid-cycling

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10.1016/0165-0327(95)00023-G

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title = "Complex and rapid-cycling in bipolar children and adolescents: a preliminary study",

abstract = "26 subjects aged 7-18 years were studied. Diagnoses of bipolar disorders were established using the Kiddie-Schedule for Affective Disorders and Schizophrenia-Present Episode Version-1986 modified for DSM-III-R criteria and for rating the number and duration of manic and hypomanic episodes. Complex cycling patterns were observed. These included numerous brief episodes suggesting continuous rapid-cycling in 80.8% of cases. Mean age of onset was early (8.5 ± 4.4 years). Psychotic phenomena, suicidality, hyperactivity and 'mixed mania' were highly prevalent. Data in this report provide support for complex and rapid-cycling patterns in childhood onset bipolar disorder.",

keywords = "Adolescent, Bipolar affective disorder, Child, Hyperactivity, Mixed mania, Rapid-cycling",

author = "Barbara Geller and Kai Sun and Betsy Zimerman and Joan Luby and Jeanne Frazier and Marlene Williams",

note = "Funding Information: This work was supported in part by National Institute on Drug Abuse Grant ROl DA04844 to B. Geller. The data presented in this communication were the pilot data for National Institute of Mental Health Grant ROl MH 53063 {\textquoteleft}Phenomenology and Course of Pediatric Bipolar Disorders{\textquoteright} to B. Geller.",

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doi = "10.1016/0165-0327(95)00023-G",

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AU - Sun, Kai

AU - Zimerman, Betsy

AU - Luby, Joan

AU - Frazier, Jeanne

AU - Williams, Marlene

N1 - Funding Information: This work was supported in part by National Institute on Drug Abuse Grant ROl DA04844 to B. Geller. The data presented in this communication were the pilot data for National Institute of Mental Health Grant ROl MH 53063 ‘Phenomenology and Course of Pediatric Bipolar Disorders’ to B. Geller.

PY - 1995/8/18

Y1 - 1995/8/18

N2 - 26 subjects aged 7-18 years were studied. Diagnoses of bipolar disorders were established using the Kiddie-Schedule for Affective Disorders and Schizophrenia-Present Episode Version-1986 modified for DSM-III-R criteria and for rating the number and duration of manic and hypomanic episodes. Complex cycling patterns were observed. These included numerous brief episodes suggesting continuous rapid-cycling in 80.8% of cases. Mean age of onset was early (8.5 ± 4.4 years). Psychotic phenomena, suicidality, hyperactivity and 'mixed mania' were highly prevalent. Data in this report provide support for complex and rapid-cycling patterns in childhood onset bipolar disorder.

AB - 26 subjects aged 7-18 years were studied. Diagnoses of bipolar disorders were established using the Kiddie-Schedule for Affective Disorders and Schizophrenia-Present Episode Version-1986 modified for DSM-III-R criteria and for rating the number and duration of manic and hypomanic episodes. Complex cycling patterns were observed. These included numerous brief episodes suggesting continuous rapid-cycling in 80.8% of cases. Mean age of onset was early (8.5 ± 4.4 years). Psychotic phenomena, suicidality, hyperactivity and 'mixed mania' were highly prevalent. Data in this report provide support for complex and rapid-cycling patterns in childhood onset bipolar disorder.

KW - Adolescent

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KW - Child

KW - Hyperactivity

KW - Mixed mania

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Complex and rapid-cycling in bipolar children and adolescents: a preliminary study

Abstract

Keywords

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