Complete nucleotide sequence of the AIDS virus, HTLV-III

Lee Ratner; William Haseltine; Roberto Patarca; Kenneth J. Livak; Bruno Starcich; Steven F. Josephs; Ellen R. Doran; J. Antoni Rafalski; Erik A. Whitehorn; Kirk Baumeister; Lucinda Ivanoff; Stephen R. Petteway; Mark L. Pearson; James A. Lautenberger; Takis S. Papas; John Ghrayeb; Nancy T. Chang; Robert C. Gallo; Flossie Wong-Staal

doi:10.1038/313277a0

Complete nucleotide sequence of the AIDS virus, HTLV-III

Lee Ratner
, William Haseltine
, Roberto Patarca
, Kenneth J. Livak
, Bruno Starcich
, Steven F. Josephs
, Ellen R. Doran
, J. Antoni Rafalski
, Erik A. Whitehorn
, Kirk Baumeister
, Lucinda Ivanoff
, Stephen R. Petteway
, Mark L. Pearson
, James A. Lautenberger
, Takis S. Papas
, John Ghrayeb
, Nancy T. Chang
, Robert C. Gallo
, Flossie Wong-Staal

Research output: Contribution to journal › Article › peer-review

1990 Scopus citations

Abstract

The complete nucleotide sequence of two human T-cell leukaemia type III (HTLV-III) proviral DNAs each have four long open reading frames, the first two corresponding to the gag and pol genes. The fourth open reading frame encodes two functional polypeptides, a large precursor of the major envelope glycoprotein and a smaller protein derived from the 3′-terminus long open reading frame analogous to the long open reading frame (lor) product of HTLV-I and -II.

Original language	English
Pages (from-to)	277-284
Number of pages	8
Journal	Nature
Volume	313
Issue number	6000
DOIs	https://doi.org/10.1038/313277a0
State	Published - 1985

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Ratner, L., Haseltine, W., Patarca, R., Livak, K. J., Starcich, B., Josephs, S. F., Doran, E. R., Rafalski, J. A., Whitehorn, E. A., Baumeister, K., Ivanoff, L., Petteway, S. R., Pearson, M. L., Lautenberger, J. A., Papas, T. S., Ghrayeb, J., Chang, N. T., Gallo, R. C., & Wong-Staal, F. (1985). Complete nucleotide sequence of the AIDS virus, HTLV-III. Nature, 313(6000), 277-284. https://doi.org/10.1038/313277a0

@article{32dec5c9a25a48a6906db9100822e9e8,

title = "Complete nucleotide sequence of the AIDS virus, HTLV-III",

abstract = "The complete nucleotide sequence of two human T-cell leukaemia type III (HTLV-III) proviral DNAs each have four long open reading frames, the first two corresponding to the gag and pol genes. The fourth open reading frame encodes two functional polypeptides, a large precursor of the major envelope glycoprotein and a smaller protein derived from the 3′-terminus long open reading frame analogous to the long open reading frame (lor) product of HTLV-I and -II.",

author = "Lee Ratner and William Haseltine and Roberto Patarca and Livak, \{Kenneth J.\} and Bruno Starcich and Josephs, \{Steven F.\} and Doran, \{Ellen R.\} and Rafalski, \{J. Antoni\} and Whitehorn, \{Erik A.\} and Kirk Baumeister and Lucinda Ivanoff and Petteway, \{Stephen R.\} and Pearson, \{Mark L.\} and Lautenberger, \{James A.\} and Papas, \{Takis S.\} and John Ghrayeb and Chang, \{Nancy T.\} and Gallo, \{Robert C.\} and Flossie Wong-Staal",

year = "1985",

doi = "10.1038/313277a0",

language = "English",

volume = "313",

pages = "277--284",

journal = "Nature",

issn = "0028-0836",

number = "6000",

}

Ratner, L, Haseltine, W, Patarca, R, Livak, KJ, Starcich, B, Josephs, SF, Doran, ER, Rafalski, JA, Whitehorn, EA, Baumeister, K, Ivanoff, L, Petteway, SR, Pearson, ML, Lautenberger, JA, Papas, TS, Ghrayeb, J, Chang, NT, Gallo, RC & Wong-Staal, F 1985, 'Complete nucleotide sequence of the AIDS virus, HTLV-III', Nature, vol. 313, no. 6000, pp. 277-284. https://doi.org/10.1038/313277a0

TY - JOUR

T1 - Complete nucleotide sequence of the AIDS virus, HTLV-III

AU - Ratner, Lee

AU - Haseltine, William

AU - Patarca, Roberto

AU - Livak, Kenneth J.

AU - Starcich, Bruno

AU - Josephs, Steven F.

AU - Doran, Ellen R.

AU - Rafalski, J. Antoni

AU - Whitehorn, Erik A.

AU - Baumeister, Kirk

AU - Ivanoff, Lucinda

AU - Petteway, Stephen R.

AU - Pearson, Mark L.

AU - Lautenberger, James A.

AU - Papas, Takis S.

AU - Ghrayeb, John

AU - Chang, Nancy T.

AU - Gallo, Robert C.

AU - Wong-Staal, Flossie

PY - 1985

Y1 - 1985

N2 - The complete nucleotide sequence of two human T-cell leukaemia type III (HTLV-III) proviral DNAs each have four long open reading frames, the first two corresponding to the gag and pol genes. The fourth open reading frame encodes two functional polypeptides, a large precursor of the major envelope glycoprotein and a smaller protein derived from the 3′-terminus long open reading frame analogous to the long open reading frame (lor) product of HTLV-I and -II.

AB - The complete nucleotide sequence of two human T-cell leukaemia type III (HTLV-III) proviral DNAs each have four long open reading frames, the first two corresponding to the gag and pol genes. The fourth open reading frame encodes two functional polypeptides, a large precursor of the major envelope glycoprotein and a smaller protein derived from the 3′-terminus long open reading frame analogous to the long open reading frame (lor) product of HTLV-I and -II.

UR - https://www.scopus.com/pages/publications/0021912920

U2 - 10.1038/313277a0

DO - 10.1038/313277a0

M3 - Article

C2 - 2578615

AN - SCOPUS:0021912920

SN - 0028-0836

VL - 313

SP - 277

EP - 284

JO - Nature

JF - Nature

IS - 6000

ER -

Complete nucleotide sequence of the AIDS virus, HTLV-III

Abstract

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