Comparison of ultrasound scattering behavior of Optison® and a liquid perfluorocarbon nanoparticle contrast agent

M. S. Hughes; J. N. Marsh; A. K. Woodson; R. W. Fuhrhop; G. M. Lanza; S. A. Wickline

Comparison of ultrasound scattering behavior of Optison® and a liquid perfluorocarbon nanoparticle contrast agent

M. S. Hughes, J. N. Marsh, A. K. Woodson, R. W. Fuhrhop, G. M. Lanza, S. A. Wickline

Research output: Contribution to journal › Conference article › peer-review

Abstract

The Optison attenuation coefficient exhibits a single peak between 1 and 3 MHz. The exact peak location, height and width vary significantly with experimental conditions. In contrast, the PFOB emulsion does not exhibit any of these effects, which strongly shows that microbubble formation through perfluorocarbon phase conversion may not contribute in a measurable manner to the acoustic properties of the liquid perfluorocarbon nanoparticle contrast agent over the range of experimental parameters considered.

Original language	English
Pages (from-to)	1965-1968
Number of pages	4
Journal	Proceedings of the IEEE Ultrasonics Symposium
Volume	2
State	Published - 2002
Event	2002 IEEE Ultrasonics Symposium - Munich, Germany Duration: Oct 8 2002 → Oct 11 2002

Cite this

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title = "Comparison of ultrasound scattering behavior of Optison{\textregistered} and a liquid perfluorocarbon nanoparticle contrast agent",

abstract = "The Optison attenuation coefficient exhibits a single peak between 1 and 3 MHz. The exact peak location, height and width vary significantly with experimental conditions. In contrast, the PFOB emulsion does not exhibit any of these effects, which strongly shows that microbubble formation through perfluorocarbon phase conversion may not contribute in a measurable manner to the acoustic properties of the liquid perfluorocarbon nanoparticle contrast agent over the range of experimental parameters considered.",

author = "Hughes, {M. S.} and Marsh, {J. N.} and Woodson, {A. K.} and Fuhrhop, {R. W.} and Lanza, {G. M.} and Wickline, {S. A.}",

year = "2002",

language = "English",

volume = "2",

pages = "1965--1968",

journal = "Proceedings of the IEEE Ultrasonics Symposium",

issn = "1051-0117",

note = "2002 IEEE Ultrasonics Symposium ; Conference date: 08-10-2002 Through 11-10-2002",

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TY - JOUR

T1 - Comparison of ultrasound scattering behavior of Optison® and a liquid perfluorocarbon nanoparticle contrast agent

AU - Hughes, M. S.

AU - Marsh, J. N.

AU - Woodson, A. K.

AU - Fuhrhop, R. W.

AU - Lanza, G. M.

AU - Wickline, S. A.

PY - 2002

Y1 - 2002

N2 - The Optison attenuation coefficient exhibits a single peak between 1 and 3 MHz. The exact peak location, height and width vary significantly with experimental conditions. In contrast, the PFOB emulsion does not exhibit any of these effects, which strongly shows that microbubble formation through perfluorocarbon phase conversion may not contribute in a measurable manner to the acoustic properties of the liquid perfluorocarbon nanoparticle contrast agent over the range of experimental parameters considered.

AB - The Optison attenuation coefficient exhibits a single peak between 1 and 3 MHz. The exact peak location, height and width vary significantly with experimental conditions. In contrast, the PFOB emulsion does not exhibit any of these effects, which strongly shows that microbubble formation through perfluorocarbon phase conversion may not contribute in a measurable manner to the acoustic properties of the liquid perfluorocarbon nanoparticle contrast agent over the range of experimental parameters considered.

UR - http://www.scopus.com/inward/record.url?scp=0036990358&partnerID=8YFLogxK

M3 - Conference article

AN - SCOPUS:0036990358

SN - 1051-0117

VL - 2

SP - 1965

EP - 1968

JO - Proceedings of the IEEE Ultrasonics Symposium

JF - Proceedings of the IEEE Ultrasonics Symposium

T2 - 2002 IEEE Ultrasonics Symposium

Y2 - 8 October 2002 through 11 October 2002

ER -

Comparison of ultrasound scattering behavior of Optison® and a liquid perfluorocarbon nanoparticle contrast agent

Abstract

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