Comparison of inversion recovery asymmetrical spin-echo EPI and gradient-echo EPI for brain motor activation study

Jie Zheng, James C. Ehrhardt, Ted Cizadlo, William T.C. Yuh

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

An inversion recovery asymmetric spin-echo (IR-ASE) echo-planar imaging (EPI) sequence has been developed for functional studies of the brain. This technique uses an 180°inversion pulse with a long inversion time (TI) to suppress the pulsatile cerebrospinal fluid and an asymmetric spin-echo readout to obtain activation signals from brain capillaries. Because gradient-echo sequences are most sensitive to large vessels, motor cortex activation studies using a gradient-echo technique also were conducted for comparison with the IR-ASE method. The results suggest that the IR-ASE pulse sequence may be a useful complement to the gradient-echo technique for the study of neuronal activity of the human brain.

Original languageEnglish
Pages (from-to)843-847
Number of pages5
JournalJournal of Magnetic Resonance Imaging
Volume7
Issue number5
DOIs
StatePublished - Sep 1 1997

Keywords

  • Asymmetric spin echo
  • Echo planar imaging
  • Functional MR
  • Inversion recovery
  • Microvascular
  • Motor cortex activation

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