TY - JOUR
T1 - Comparison of Intraocular Irrigating Solutions in Pars Plana Vitrectomy
AU - Rosenfeld, Steven I.
AU - Waltman, Stephen R.
AU - Olk, R. Joseph
AU - Gordon, Mae
N1 - Funding Information:
Supported in part by a grant from Research To Prevent Blindness, Inc., New York, New York (Department of Ophthalmology) and a grant from The Monsanto Company, SI. Louis, Missouri (SRW).
PY - 1986
Y1 - 1986
N2 - A prospective, randomized, masked clinical study was conducted to examine the effects of pars plana vitrectomy on the corneal endothelium comparing Balanced Salt Solution (BSS®) to BSS-Plus® as an intraocular irrigating solution. Seventy-one patients were followed for at least six months. A significant 6.9% decrease in endothelial cell density was observed among all patients at six months postoperatively, compared to preoperative values, using the contralateral eye as a control. However, no significant difference in endothelial cell loss was found between BSS® and BSS-Plus® eyes. Both aphakic eyes and those undergoing lensectomy (with vitrectomy) showed a significantly greater reduction of endothelial cell density at six months compared to phakic eyes. No significant difference in corneal thickness was observed at six months postoperatively compared to preoperative values. For the one-year duration of our study BSS® was as efficacious in preserving the integrity of the corneal endothelium as was BSS-Plus®.
AB - A prospective, randomized, masked clinical study was conducted to examine the effects of pars plana vitrectomy on the corneal endothelium comparing Balanced Salt Solution (BSS®) to BSS-Plus® as an intraocular irrigating solution. Seventy-one patients were followed for at least six months. A significant 6.9% decrease in endothelial cell density was observed among all patients at six months postoperatively, compared to preoperative values, using the contralateral eye as a control. However, no significant difference in endothelial cell loss was found between BSS® and BSS-Plus® eyes. Both aphakic eyes and those undergoing lensectomy (with vitrectomy) showed a significantly greater reduction of endothelial cell density at six months compared to phakic eyes. No significant difference in corneal thickness was observed at six months postoperatively compared to preoperative values. For the one-year duration of our study BSS® was as efficacious in preserving the integrity of the corneal endothelium as was BSS-Plus®.
KW - Balanced Salt Solution®
KW - corneal thickness
KW - endothelial cell density
KW - pars planalensectomy
KW - pars planavitrectomy
UR - http://www.scopus.com/inward/record.url?scp=0022589430&partnerID=8YFLogxK
U2 - 10.1016/S0161-6420(86)33790-4
DO - 10.1016/S0161-6420(86)33790-4
M3 - Article
C2 - 3513079
AN - SCOPUS:0022589430
SN - 0161-6420
VL - 93
SP - 109
EP - 115
JO - Ophthalmology
JF - Ophthalmology
IS - 1
ER -